10 Best Non Aspirin of 2025

Last updated on 12/19/2025
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Best Choice
1
GeriCare Aspirin Tablets 325mg - Pain Reliever and Fever Reducer Uncoated Aspirins for Adults & Kids 12+ (NSAID) Great for Headache, Toothache, Arthritis, Menstrual & Muscle Pain (Bottle of 1,000)

GeriCare Aspirin Tablets 325mg - Pain Reliever and Fever Reducer Uncoated Aspirins for Adults & Kids 12+ (NSAID) Great for Headache, Toothache, Arthritis, Menstrual & Muscle Pain (Bottle of 1,000)

GeriCare
6% OffFree Shipping
Why we love it
  • Effective pain relief solution.
  • No synthetic coatings or fillers.
  • Large supply for the family.
Main Highlights
  • REGULAR STRENGTH 325mg ASPIRIN [NSAID]: The GeriCare Aspirins offer 325mg of pure aspirin per tablet which is the optimal amount for everyday aches and pains. Just the recommended, regular-strength dose any adult or teenager can fully benefit from. [NSAID - nonsteroidal anti-inflammatory drug. Compare to the active ingredient of Bayer Aspirin.]
  • PURE, UNCOATED ASPIRINS FOR FASTER ABSORPTION: Completely free of synthetic coating, flavorings, dyes or other fillers [we just use corn starch as a binder], our uncoated aspirin tablets make a safe choice for anyone, especially those who prefer a purer painkiller. Plus, non-coated aspirins are faster and easier absorbed than the coated ones for that immediate pain relief you long for.
  • EXTREMELY VERSATILE & EFFECTIVE FOR FEVER, PAINS & ACHES: Our aspirins for adults and kids aged 12+, work wonders on reducing fever and fighting the symptoms of common cold. They also offer temporary relief from headache, toothache, muscle pain, arthritis and period cramps while they can also provide great anti-inflammatory care for an array of conditions.
  • 1,000 ASPIRIN TABLETS PER BOTTLE TO LAST A LONG, LONG TIME: With no less than 1,000 tablets per bottle, you may rest assured that you will not run out of aspirin pills anytime soon. Ideal for the whole family to use. DOSE: Take 1-2 tablets every 4 hours while symptoms last. Do not take more than 12 tablets in 24 hours, unless directed by a doctor.
  • WITH GERICARE’S SEAL OF EXCELLENCE: With 30 years of experience in creating the highest quality supplements and medical supplies that can make a true difference in your life, you have every good reason to trust GeriCare for your wellbeing. Our expert team of health professionals is always at your disposal for any questions you may have!
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9.7
Exceptional
9.7
Exceptional
GeriCare

GeriCare Aspirin Tablets 325mg - Pain Reliever and Fever Reducer Uncoated Aspirins for Adults & Kids 12+ (NSAID) Great for Headache, Toothache, Arthritis, Menstrual & Muscle Pain (Bottle of 1,000)

6% OffFree Shipping
Why we love it
  • Effective pain relief solution.
  • No synthetic coatings or fillers.
  • Large supply for the family.
Main Highlights
  • REGULAR STRENGTH 325mg ASPIRIN [NSAID]: The GeriCare Aspirins offer 325mg of pure aspirin per tablet which is the optimal amount for everyday aches and pains. Just the recommended, regular-strength dose any adult or teenager can fully benefit from. [NSAID - nonsteroidal anti-inflammatory drug. Compare to the active ingredient of Bayer Aspirin.]
  • PURE, UNCOATED ASPIRINS FOR FASTER ABSORPTION: Completely free of synthetic coating, flavorings, dyes or other fillers [we just use corn starch as a binder], our uncoated aspirin tablets make a safe choice for anyone, especially those who prefer a purer painkiller. Plus, non-coated aspirins are faster and easier absorbed than the coated ones for that immediate pain relief you long for.
  • EXTREMELY VERSATILE & EFFECTIVE FOR FEVER, PAINS & ACHES: Our aspirins for adults and kids aged 12+, work wonders on reducing fever and fighting the symptoms of common cold. They also offer temporary relief from headache, toothache, muscle pain, arthritis and period cramps while they can also provide great anti-inflammatory care for an array of conditions.
  • 1,000 ASPIRIN TABLETS PER BOTTLE TO LAST A LONG, LONG TIME: With no less than 1,000 tablets per bottle, you may rest assured that you will not run out of aspirin pills anytime soon. Ideal for the whole family to use. DOSE: Take 1-2 tablets every 4 hours while symptoms last. Do not take more than 12 tablets in 24 hours, unless directed by a doctor.
  • WITH GERICARE’S SEAL OF EXCELLENCE: With 30 years of experience in creating the highest quality supplements and medical supplies that can make a true difference in your life, you have every good reason to trust GeriCare for your wellbeing. Our expert team of health professionals is always at your disposal for any questions you may have!
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Value for Money
2
PhysiciansCare Sinus Decongestant Congestion Medication, 2 Tablets Per Packet, Box Of 50

PhysiciansCare Sinus Decongestant Congestion Medication, 2 Tablets Per Packet, Box Of 50

PhysiciansCare
13% OffFree Shipping
Why we love it
  • Effective sinus relief solution.
  • Convenient single-tablet packaging.
  • Non-drowsy, easy-to-swallow formula.
Main Highlights
  • Compare to the active ingredients in Sudafed PE
  • Coated, easy-to-swallow tablets.
  • 50 single-tablet packets come in a perforated dispenser box for easy access.
  • Relieves sinus pressure and congestion.
  • Non-drowsy formula.
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9.6
Superb
9.6
Superb
PhysiciansCare

PhysiciansCare Sinus Decongestant Congestion Medication, 2 Tablets Per Packet, Box Of 50

13% OffFree Shipping
Why we love it
  • Effective sinus relief solution.
  • Convenient single-tablet packaging.
  • Non-drowsy, easy-to-swallow formula.
Main Highlights
  • Compare to the active ingredients in Sudafed PE
  • Coated, easy-to-swallow tablets.
  • 50 single-tablet packets come in a perforated dispenser box for easy access.
  • Relieves sinus pressure and congestion.
  • Non-drowsy formula.
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3
GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count

GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count

GoodSense
Free Shipping
Why we love it
  • Effective pain relief solution.
  • Trusted active ingredient formula.
  • Fast-acting for various pains.
Main Highlights
  • ACTIVE INGREDIENT: GoodSense Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol Caplets
  • GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps. It also temporarily reduces fever
  • USE: Acetaminophen may be used as a pain reliever and fever reducer for adults and children 12 years and over
  • PAIN: Pain may begin with an injury or illness, but could also originate with anything from a bad mattress to arthritis
  • ACUTE PAIN: Acute pain acts as an alarm such as with a bee sting or stubbing your toe and can last for a few moments or for longer
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9.4
Superb
9.4
Superb
GoodSense

GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count

Free Shipping
Why we love it
  • Effective pain relief solution.
  • Trusted active ingredient formula.
  • Fast-acting for various pains.
Main Highlights
  • ACTIVE INGREDIENT: GoodSense Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol Caplets
  • GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps. It also temporarily reduces fever
  • USE: Acetaminophen may be used as a pain reliever and fever reducer for adults and children 12 years and over
  • PAIN: Pain may begin with an injury or illness, but could also originate with anything from a bad mattress to arthritis
  • ACUTE PAIN: Acute pain acts as an alarm such as with a bee sting or stubbing your toe and can last for a few moments or for longer
Show More
4
Excedrin Tension Headache Relief Caplets, Acetaminophen 500mg, Caffeine 65mg, Pain Reliever, Aspirin-Free, 100 Count

Excedrin Tension Headache Relief Caplets, Acetaminophen 500mg, Caffeine 65mg, Pain Reliever, Aspirin-Free, 100 Count

Excedrin
19% OffFree Shipping
Why we love it
  • Aspirin-free formula offers comfort.
  • Fast relief from tension headaches.
  • Convenient caplet form for ease.
Main Highlights
  • One bottle of 100 caplets of Excedrin Tension Headache Relief Caplets Without Aspirin for Head, Neck and Shoulder Pain Relief
  • Aspirin-free tension headache pain medicine that quickly relieves headaches and pain caused by tension and stress
  • Delivers muscle ache, shoulder and neck pain relief
  • Combines acetaminophen with caffeine to temporarily relieve pain caused by headaches and muscle aches
  • Contains a trusted formula that combines a pain reliever and an amplifier
  • Effectively relieves tension-type headaches in convenient caplet form
  • HSA and FSA eligible product
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9.2
Superb
9.2
Superb
Excedrin

Excedrin Tension Headache Relief Caplets, Acetaminophen 500mg, Caffeine 65mg, Pain Reliever, Aspirin-Free, 100 Count

19% OffFree Shipping
Why we love it
  • Aspirin-free formula offers comfort.
  • Fast relief from tension headaches.
  • Convenient caplet form for ease.
Main Highlights
  • One bottle of 100 caplets of Excedrin Tension Headache Relief Caplets Without Aspirin for Head, Neck and Shoulder Pain Relief
  • Aspirin-free tension headache pain medicine that quickly relieves headaches and pain caused by tension and stress
  • Delivers muscle ache, shoulder and neck pain relief
  • Combines acetaminophen with caffeine to temporarily relieve pain caused by headaches and muscle aches
  • Contains a trusted formula that combines a pain reliever and an amplifier
  • Effectively relieves tension-type headaches in convenient caplet form
  • HSA and FSA eligible product
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5
HealthA2Z® Pain Relief Extended Release | Acetaminophen 650mg | 8 Hours | Arthiritis Pain | Pain Reliever - Fever Reducer | Contains no Aspirin | (250 Caplets)

HealthA2Z® Pain Relief Extended Release | Acetaminophen 650mg | 8 Hours | Arthiritis Pain | Pain Reliever - Fever Reducer | Contains no Aspirin | (250 Caplets)

HealthA2Z
Free Shipping
Why we love it
  • Effective Pain Management Solution.
  • Long-Lasting Relief with Convenience.
  • Ideal for Arthritis Discomfort.
Main Highlights
  • Long-Lasting Pain Relief: Formulated with Acetaminophen 650mg to provide up to 8 hours of relief from minor aches and pains.
  • Targets Multiple Discomforts: Helps temporarily relieve pain associated with arthritis, backache, headache, muscular aches, toothache, and minor joint pain.
  • Dual Action Support: Acts as both a pain reliever and fever reducer for everyday comfort and wellness.
  • Gentle on Stomach: Contains no aspirin, providing an alternative option for those avoiding NSAIDs.
  • Value Size: Includes 250 extended-release caplets—ideal for home, office, or long-term use.
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9.1
Superb
9.1
Superb
HealthA2Z

HealthA2Z® Pain Relief Extended Release | Acetaminophen 650mg | 8 Hours | Arthiritis Pain | Pain Reliever - Fever Reducer | Contains no Aspirin | (250 Caplets)

Free Shipping
Why we love it
  • Effective Pain Management Solution.
  • Long-Lasting Relief with Convenience.
  • Ideal for Arthritis Discomfort.
Main Highlights
  • Long-Lasting Pain Relief: Formulated with Acetaminophen 650mg to provide up to 8 hours of relief from minor aches and pains.
  • Targets Multiple Discomforts: Helps temporarily relieve pain associated with arthritis, backache, headache, muscular aches, toothache, and minor joint pain.
  • Dual Action Support: Acts as both a pain reliever and fever reducer for everyday comfort and wellness.
  • Gentle on Stomach: Contains no aspirin, providing an alternative option for those avoiding NSAIDs.
  • Value Size: Includes 250 extended-release caplets—ideal for home, office, or long-term use.
Show More
6
Doan's Backache Pain Reliever - Extra Strength - 24 Count Caplets Per Box - Pack of 2

Doan's Backache Pain Reliever - Extra Strength - 24 Count Caplets Per Box - Pack of 2

Doans
9% Off
Why we love it
  • Powerful relief for back pain.
  • Fast-acting, extra strength formula.
  • Trusted brand for consistent results.
Main Highlights
  • Doan's backache pain reliever
  • Extra strength - relieves backache pain
  • Doan's Backache Pain Reliever
  • Extra Strength - Relieves Backache Pain
Show More
9.1
Superb
9.1
Superb
Doans

Doan's Backache Pain Reliever - Extra Strength - 24 Count Caplets Per Box - Pack of 2

9% Off
Why we love it
  • Powerful relief for back pain.
  • Fast-acting, extra strength formula.
  • Trusted brand for consistent results.
Main Highlights
  • Doan's backache pain reliever
  • Extra strength - relieves backache pain
  • Doan's Backache Pain Reliever
  • Extra Strength - Relieves Backache Pain
Show More
7
SC Refill Extra Strength Non-Aspirin, 10x2/box

SC Refill Extra Strength Non-Aspirin, 10x2/box

First Aid Only
8% OffFree Shipping
Why we love it
  • Efficient supply organization guaranteed.
  • Safe and sterile packaging ensured.
  • Perfect for on-the-go relief.
Main Highlights
  • SmartCompliance Refill: Keeps first aid supplies organized and stocked efficiently.
  • Extra Strength Formula: Provides temporary relief for headaches, muscle aches, arthritis, toothaches, and menstrual cramps.
  • Tamper-Evident Packaging: Ensures safety and sterility of each dose.
  • Convenient & Portable: Includes 10 packets, each containing 2 tablets for easy storage and use.
  • Ideal for First Aid Kits: Compatible with various First Aid Only SmartCompliance cabinets.
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8.9
Excellent
8.9
Excellent
First Aid Only

SC Refill Extra Strength Non-Aspirin, 10x2/box

8% OffFree Shipping
Why we love it
  • Efficient supply organization guaranteed.
  • Safe and sterile packaging ensured.
  • Perfect for on-the-go relief.
Main Highlights
  • SmartCompliance Refill: Keeps first aid supplies organized and stocked efficiently.
  • Extra Strength Formula: Provides temporary relief for headaches, muscle aches, arthritis, toothaches, and menstrual cramps.
  • Tamper-Evident Packaging: Ensures safety and sterility of each dose.
  • Convenient & Portable: Includes 10 packets, each containing 2 tablets for easy storage and use.
  • Ideal for First Aid Kits: Compatible with various First Aid Only SmartCompliance cabinets.
Show More
8
Medique @ Home 70433 Extra Strength APAP Tablets, Non-Aspirin, 50 Packets (2 Tablets per Packet) Total-100 Count

Medique @ Home 70433 Extra Strength APAP Tablets, Non-Aspirin, 50 Packets (2 Tablets per Packet) Total-100 Count

Medique
36% OffFree Shipping
Why we love it
  • Trusted brand for home care.
  • Effective pain relief solution.
  • User-friendly and easy to swallow.
Main Highlights
  • Medique @ Home the brands that work now work at home
  • Each tablet contains Acetaminophen 500mg
  • Easy to swallow film coated tablets
  • Compare active ingredient to Extra Strength Tylenol
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8.7
Excellent
8.7
Excellent
Medique

Medique @ Home 70433 Extra Strength APAP Tablets, Non-Aspirin, 50 Packets (2 Tablets per Packet) Total-100 Count

36% OffFree Shipping
Why we love it
  • Trusted brand for home care.
  • Effective pain relief solution.
  • User-friendly and easy to swallow.
Main Highlights
  • Medique @ Home the brands that work now work at home
  • Each tablet contains Acetaminophen 500mg
  • Easy to swallow film coated tablets
  • Compare active ingredient to Extra Strength Tylenol
Show More
9
HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))

HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))

HealthA2Z
Free Shipping
Why we love it
  • Fast relief for various pains.
  • Effective fever reduction support.
  • Gentle on sensitive stomachs.
Main Highlights
  • ✅ Fast, Effective Pain Relief: Each caplet contains 500 mg of acetaminophen to relieve headaches, backaches, muscle aches, toothaches, and menstrual pain.
  • ✅ Reduces Fever: Helps temporarily reduce fever and provide comfort during colds or flu.
  • ✅ Gentle on Stomach: Contains no aspirin, caffeine, or ibuprofen — suitable for those with sensitive stomachs.
  • ✅ Trusted Everyday Relief: Safe and effective when used as directed for adults and children 12 years and older.
Show More
8.7
Excellent
8.7
Excellent
HealthA2Z

HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))

Free Shipping
Why we love it
  • Fast relief for various pains.
  • Effective fever reduction support.
  • Gentle on sensitive stomachs.
Main Highlights
  • ✅ Fast, Effective Pain Relief: Each caplet contains 500 mg of acetaminophen to relieve headaches, backaches, muscle aches, toothaches, and menstrual pain.
  • ✅ Reduces Fever: Helps temporarily reduce fever and provide comfort during colds or flu.
  • ✅ Gentle on Stomach: Contains no aspirin, caffeine, or ibuprofen — suitable for those with sensitive stomachs.
  • ✅ Trusted Everyday Relief: Safe and effective when used as directed for adults and children 12 years and older.
Show More
10
Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Headache, Muscular Aches, Arthritis, Backache and More, 100 Count (Pack of 1)

Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Headache, Muscular Aches, Arthritis, Backache and More, 100 Count (Pack of 1)

Amazon Basic Care
Free Shipping
Why we love it
  • Powerful pain relief option.
  • Fast-acting, effective formula.
  • Gluten-free coated tablets.
Main Highlights
  • ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care Ibuprofen Tablets is 200 mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), pain reliever and fever reducer; compare to the active ingredient of Advil
  • PAIN RELIEF: Use Ibuprofen to temporarily relieve minor aches and pains due to headache, muscular aches, arthritis, toothache, backache, the common cold and menstrual cramps
  • PAIN RELIEF: Proven pain relief without a prescription
  • IBUPROFEN is the number one doctor recommended OTC active ingredient for back pain (of U.S. physicians surveyed by an independent market research firm)
  • COATED TABLETS: These coated tablets, with the active ingredient ibuprofen 200 mg, are a gluten free choice to relieve minor body aches and pains
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8.7
Excellent
8.7
Excellent
Amazon Basic Care

Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Headache, Muscular Aches, Arthritis, Backache and More, 100 Count (Pack of 1)

Free Shipping
Why we love it
  • Powerful pain relief option.
  • Fast-acting, effective formula.
  • Gluten-free coated tablets.
Main Highlights
  • ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care Ibuprofen Tablets is 200 mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), pain reliever and fever reducer; compare to the active ingredient of Advil
  • PAIN RELIEF: Use Ibuprofen to temporarily relieve minor aches and pains due to headache, muscular aches, arthritis, toothache, backache, the common cold and menstrual cramps
  • PAIN RELIEF: Proven pain relief without a prescription
  • IBUPROFEN is the number one doctor recommended OTC active ingredient for back pain (of U.S. physicians surveyed by an independent market research firm)
  • COATED TABLETS: These coated tablets, with the active ingredient ibuprofen 200 mg, are a gluten free choice to relieve minor body aches and pains
Show More