10 Best Weed Killer of 2025

Last updated on 08/02/2025

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Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Pump 'N Go 2 Sprayer, 1.33 gal.

Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Pump 'N Go 2 Sprayer, 1.33 gal.

Long-lasting weed protection solution.
Effective against various tough weeds.
User-friendly sprayer with extended reach.

Main Highlights

Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Pump 'N Go 2 Sprayer provides one-step weed protection for up to 12 months
Our weed control kills and prevents many types of tough weeds and grasses for up to 12 months, including clover, dandelion, large and smooth crabgrass, poison ivy, and other broadleaf weeds, grassy weeds and brush
Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Pump 'N Go 2 Sprayer is rainproof in as fast as 30 minutes and produces visible results in hours
Use this weed preventer where you want to kill existing weeds AND prevent new weeds for up to 1 year, such as cracks and crevices in driveways, sidewalks, and walkways, patios, paths, and under decks, gravel areas, and other non-lawn areas
The Pump ‘N Go 2 Sprayer with an extendable wand provides up to 10 minutes of continuous spray and provides greater accuracy without bending over

Roundup Dual Action Weed & Grass Killer Plus 4 Month Preventer with Sure Shot Wand, 1 gal.

Roundup Dual Action Weed & Grass Killer Plus 4 Month Preventer with Sure Shot Wand, 1 gal.

17% OffFree Shipping

Kills weeds down to roots.
Rainproof in just 30 minutes.
Sure Shot Wand for precision.

Main Highlights

Roundup Dual Action Weed & Grass Killer Plus 4 Month Preventer with Sure Shot Wand kills existing weeds and grass down to the root and prevents new weeds from growing for up to 4 months
This weed killer and preventer is rainproof in as fast as 30 minutes, and produces visible results in as fast as 6 hours
Apply this herbicide to hardscapes and landscapes - cracks and crevices in driveways, sidewalks, and patios, along fences, in mulched beds or around the base of well-established desirable plants, shrubs, or trees, and on gravel areas
All ornamental bedding plants, trees, shrubs, sod, and seed can be planted 4 months after application
The innovative protective shield of the Sure Shot Wand allows you to use Roundup Dual Action with confidence to target weeds in garden beds and landscaped areas

Roundup Poison Ivy Plus Tough Brush Killer₂ with Comfort Wand, Visible Results in Hours, 1 gal.

Roundup Poison Ivy Plus Tough Brush Killer₂ with Comfort Wand, Visible Results in Hours, 1 gal.

42% OffFree Shipping

Kills tough weeds effectively.
Rainproof in just 30 minutes.
Comfort wand for easy use.

Main Highlights

Roundup Poison Ivy Plus Tough Brush Killer₂ with Comfort Wand is an exclusive formula that kills poison ivy, poison oak, poison sumac, wild blackberry, kudzu, and all types of tough weeds
Rainproof in as fast as 30 minutes and produces visible results in hours
Allows for planting 1 to 30 days after application (see booklet for details)
Use this weed control in residential fields and trails, around trees or shrubs, around homes, buildings, cabins, lodges, and camp sites, along fences and foundations, on vines growing up poles or mature trees, and other areas where tough weed are invading your yard
The reusable Comfort Wand is a one-touch precision wand that makes bending down to kill weeds a thing of the past

Roundup for Lawns₁ Ready-to-Use with Extend Wand, Tough Weed Killer for Use on Northern Grasses, 1.33 gal.

Roundup for Lawns₁ Ready-to-Use with Extend Wand, Tough Weed Killer for Use on Northern Grasses, 1.33 gal.

Effective on 253 weed types.
Works immediately and rainproof.
Easy application with spray wand.

Main Highlights

Roundup For Lawns₁ is a ready-to-use tough weed killer for Northern grasses that kills weeds, roots and all (when used as directed), with up to 3 month weed control (as listed)
Kills 253 types of weeds (see inside booklet for weed list), including crabgrass, dandelion, clover, yellow nutsedge, poison ivy, chickweed, oxalis, and purslane
Roundup For Lawns₁ starts working immediately and is rainproof in 3 hours
Use this tough weed killer on listed Northern grasses, including Kentucky Bluegrass, Perennial Ryegrass, Fescue spp. including Tall, Red, and Fine Leaf Fescues, and Zoysiagrass
The easy reach extendable spray wand makes application a breeze with its continuous spray
Not available in FL, HI, LA, NY, TX, Guam, Puerto Rico, Virgin Islands

Roundup Weed and Grass Killer₄ with Pump 'N Go 2 Sprayer, Use in and Around Flower Beds, Trees & More, 1.33 gal.

Roundup Weed and Grass Killer₄ with Pump 'N Go 2 Sprayer, Use in and Around Flower Beds, Trees & More, 1.33 gal.

14% OffFree Shipping

Powerful root-killing formula.
Rainproof in just 30 minutes.
Convenient spray with accuracy.

Main Highlights

Roundup Weed & Grass Killer₄ kills tough weeds and grasses to the root, including dandelion, crabgrass, poison ivy, clover (red & white), spotted spurge, and other broadleaf weeds
It is rainproof in as fast as 30 minutes and produces visible results in hours
Allows for planting 1 to 30 days after application (see booklet for details)
Use in or around flower beds and perennial landscape plants, around trees and shrubs, on patios, walkways, and driveways, gravel, or mulch beds, along fences and foundations, and edging around foundations and retaining walls
The Pump ‘N Go 2 Sprayer with an extendable wand provides up to 10 minutes of continuous spray and provides greater accuracy without bending over

Spectracide Weed and Grass Killer, Pack of 1

Spectracide Weed and Grass Killer, Pack of 1

24% OffFree Shipping

Fast visible results guaranteed.
Convenient for outdoor spaces.
Quick rain protection included.

Main Highlights

KILLS WEEDS AND GRASSES: Use on driveways and walkways, and around fences, trees, flower beds, shrubs and other listed areas.
ACCUSHOT SPRAYER: Includes continuous power sprayer with extendable wand.
KILLS THE ROOT: Visible results as fast as 3 hours — replant new flowers, trees and shrubs the same weekend.
RAINFAST: Rainfall or watering 15 minutes after application will not wash away effectiveness.

Roundup Weed & Grass Killer₄ Refill, Use in and Around Flower Beds, Trees, Driveways, Walkways & More, 1.25 gal.

Roundup Weed & Grass Killer₄ Refill, Use in and Around Flower Beds, Trees, Driveways, Walkways & More, 1.25 gal.

20% OffFree Shipping

Effective against tough weeds.
Rainproof in just 30 minutes.
Quick refill for convenience.

Main Highlights

Roundup Weed & Grass Killer₄ kills tough weeds and grasses to the root, including dandelion, crabgrass, poison ivy, clover (red & white), spotted spurge, and other broadleaf weeds
It is rainproof in as fast as 30 minutes and produces visible results in hours
Allows for planting 1 to 30 days after application (see booklet for details)
Use in or around flower beds and perennial landscape plants, around trees and shrubs, on patios, walkways, and driveways, gravel, or mulch beds, along fences and foundations, and edging around foundations and retaining walls
Roundup Weed & Grass Killer₄ Refill is the fast and easy way to refill your Weed & Grass Killer₄

Ortho GroundClear Weed and Grass Killer with Comfort Wand, Kills Dandelions, Chickweed, Crabgrass, Moss and More in Patios and Landscapes, OMRI Listed, 1 gal.

Ortho GroundClear Weed and Grass Killer with Comfort Wand, Kills Dandelions, Chickweed, Crabgrass, Moss and More in Patios and Landscapes, OMRI Listed, 1 gal.

10% OffFree Shipping

Quick results in 15 minutes.
Rainproof within 2 hours.
Comfort Wand for precision application.

Main Highlights

People and pets may enter treated areas after spray has dried
This fast-acting weed control product absorbs on contact to produce results in just 15 minutes, and is rainproof in 2 hours (upon drying)
This weed and grass killer controls weeds in, on and around walkways and driveways, under trees, and in landscape beds; not for use on lawns or grasses you like
Apply when weeds are small, actively growing and not wet from rain, dew or irrigation
This 1 gal. container of Ortho GroundClear Weed & Grass Killer includes a Comfort Wand applicator to accurately target weeds you want to kill

Ortho WeedClear Weed Killer for Lawns with Comfort Wand, Kills More than 250 Weeds including Dandelion and Clover, 1 gal.

Ortho WeedClear Weed Killer for Lawns with Comfort Wand, Kills More than 250 Weeds including Dandelion and Clover, 1 gal.

12% OffFree Shipping

Kills weeds without harming lawn.
Effective against over 250 weeds.
Convenient spray applicator included.

Main Highlights

Weed killer for lawns: Use Ortho WeedClear Weed Killer for Lawns to kill over 250 listed weeds including dandelion and clover down to the root, without harming your lawn (when used as directed)
Fast-acting weed control: Kills listed weeds like dandelion, clover, and chickweed down to the root and gets results with 1 application
Spot treatment for weeds: Kills weeds not the lawn when used as directed - use on St. Augustinegrass (not Floratam), Bermudagrass, Centipedegrass, Zoysiagrass, Buffalograss, and Bahiagrass, Kentucky Bluegrass, Ryegrass, Tall Fescue, and Fine Fescue
Spray weed killer: Apply this lawn weed killer to small, actively growing weeds when daytime temperatures are below 90°F
Ready to use: This 1 gal. container of Ortho WeedClear Weed Killer for Lawns comes with the continuous-spray Comfort Wand applicator to easily spot treat weeds in your lawn

Southern Ag Amine 2,4-D WEED KILLER, 32oz - Quart

Southern Ag Amine 2,4-D WEED KILLER, 32oz - Quart

11% OffFree Shipping

Low application rate efficiency.
Effective on diverse weeds.
Versatile usage across locations.

Main Highlights

Low, economical use rate of 1 to 4 pints per acre
Controls many broadleaf weeds & woody plants
Use in turf, pastures, rangeland, ditch banks, fences…