10 Best Strong Laxatives For Constipation Extra Strong of 2025

Last updated on 08/10/2025

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HealthA2Z Laxative Bisacodyl 5mg | 100 Counts | Gentle and Fast Overnight Relief for Constipation

HealthA2Z Laxative Bisacodyl 5mg | 100 Counts | Gentle and Fast Overnight Relief for Constipation

Reliable overnight constipation relief.
Gently stimulates bowel muscles.
Effective in 6-12 hours.

Main Highlights

✅ The active ingredient is Bisacodyl 5mg which is a stimulant laxative.
✅ Reliable overnight relief from constipation: HealthA2Z Laxative provides reliable and predictable overnight relief by gently stimulating the intestines to encourage a morning bowel movement.
✅ Works in 6-12 hours: HealthA2Z Laxative works by gently stimulating the bowel muscles to provide reliable relief of constipation in 6-12 hours.

HealthA2Z® Woman's Gentle Laxative | Bisacodyl Stimulant Laxative 5mg | Constipation Relief | Gentle and Reliable | Overnight Relief (150 Tablets)

HealthA2Z® Woman's Gentle Laxative | Bisacodyl Stimulant Laxative 5mg | Constipation Relief | Gentle and Reliable | Overnight Relief (150 Tablets)

Main Highlights

HealthA2Z Woman's Gentle Laxative contains 5mg of Bisacodyl USP in each tablet

MiraLAX Laxative Powder, Gentle Constipation Relief for Adults, Stool Softener with PEG 3350, Nonstimulant Laxative, No Harsh Side Effects, Osmotic Laxative, 45 Dose

MiraLAX Laxative Powder, Gentle Constipation Relief for Adults, Stool Softener with PEG 3350, Nonstimulant Laxative, No Harsh Side Effects, Osmotic Laxative, 45 Dose

Gentle hydration for your system.
No harsh side effects experienced.
Physician recommended for effectiveness.

Main Highlights

UNBLOCK YOUR SYSTEM: MiraLAX, an osmotic laxative, works naturally with the water in your body to hydrate, soften, and ease stool through your colon in 1-3 days. Other stimulant laxatives stimulate the nerves to move stool through the colon immediately
NO HARSH SIDE EFFECTS: MiraLAX helps relieve your occasional constipation without causing gas, bloating, cramping, or sudden urgency
#1 PHYSICIAN RECOMMENDED: Since going on the market as an OTC laxative in 2007, MiraLAX has been the #1 Physician Recommended OTC brand of laxative
HOW TO USE: Fill bottle cap to the indicated line (white section in cap) and pour into 4 to 8 ounces of hot or cold beverage. Mix until the powder is fully dissolved and drink. MiraLAX has no added taste or grit
FREE FROM: Gluten, sugar, and preservatives

Senokot Extra Strength Natural Vegetable Laxative for Gentle Overnight Relief Occasional Constipation, 36 Count

Senokot Extra Strength Natural Vegetable Laxative for Gentle Overnight Relief Occasional Constipation, 36 Count

25% OffFree Shipping

Gentle overnight relief guaranteed.
Natural ingredients provide comfort.
Easy-to-swallow, extra strength tablets.

Main Highlights

GENTLE, DEPENDABLE, OVERNIGHT RELIEF. Senokot Extra Strength laxative tablets use a standardized senna concentrate to provide gentle, dependable overnight relief of occasional constipation. Double the strength of Senokot Regular Strength laxative tablets.
CLINICALLY PROVEN. Senokot Extra Strength Laxative Tablets provide gentle, overnight relief from occasional constipation using a natural vegetable laxative ingredient. Use for treating occasional constipation.
NATURAL VEGETABLE LAXATIVE INGREDIENT. For your comfort, the active ingredient in Senokot Extra Strength Laxative Tablets is purified senna, manufactured to high quality standards. For dependable overnight relief from occasional constipation.
HELPS RELIEVE OCCASIONAL CONSTIPATION. Senokot Extra Strength Laxative Tablets contain a natural vegetable laxative ingredient. Double the strength of Regular Strength Senokot laxative tablets
DEPENDABLE RELIEF. Like all Senokot Laxative products, Senokot Extra Strength Laxative Tablets are produced from the natural vegetable laxative ingredient senna, providing dependable, overnight relief from occasional constipation.

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives

31% OffFree Shipping

Fast relief in 15 minutes.
Targets relief where needed.
Doctor recommended for effectiveness.

Main Highlights

Includes: One (1) 28-count box of Dulcolax medicated stimulant laxative suppositories
Works fast: Dulcolax suppositories provide fast relief from constipation in as little as 15 to 60 minutes
Targets the source: Suppositories deliver the active ingredient directly into the rectum for localized relief where it's needed
Effective active ingredient: Dulcolax medicated laxative suppositories are made with 10 mg bisacodyl, which stimulates your gut muscles to move things out
On-the-go relief: Pack these compact laxative suppositories in your travel essentials to help you get back to being regular when stress and overindulgence slow you down
Doctor recommended: Dulcolax is the No. 1 doctor-recommended brand among OTC stimulant laxative brands
Comfort-shaped: These laxative suppositories are made to comfortably insert and retain to give you the relief you need

Dulcolax Stimulant Laxative Tablets, Predictable & Effective Constipation Relief, Relieves Straining & Bloating, Bisacodyl 5 mg, 50 Count

Dulcolax Stimulant Laxative Tablets, Predictable & Effective Constipation Relief, Relieves Straining & Bloating, Bisacodyl 5 mg, 50 Count

29% OffFree Shipping

Dependable constipation relief guaranteed.
Fast acting for immediate comfort.
Doctor recommended for trusted efficacy.

Main Highlights

Includes: One (1) 50-count box of Dulcolax stimulant laxative comfort-coated tablets
Dependable constipation relief: Dulcolax tablets reactivate your natural gut rhythm* for effective morning constipation relief
Works fast: Dulcolax provides constipation relief in as little as six to 12 hours, starting with just one tablet
Effective active ingredient: Dulcolax stimulant laxative tablets are made with bisacodyl, which helps increase movement in the intestines
On-the-go relief: Pack these overnight laxative pills in your travel essentials to help you get back to being regular when stress and overindulgence slow you down
Doctor recommended: Dulcolax is the No. 1 doctor-recommended brand among OTC stimulant laxative brands
Predictable relief: Provides predictable relief of hard, dry stools caused by occasional constipation and irregularity

TIME-CAP LABS, INC. Timely - Max Lax Laxatives - 90 Maximum Strength Tablets - 25mg Sennosides Laxative - Occasional Constipation Relief, Best Laxatives for Constipation Fast Acting

TIME-CAP LABS, INC.

TIME-CAP LABS, INC. Timely - Max Lax Laxatives - 90 Maximum Strength Tablets - 25mg Sennosides Laxative - Occasional Constipation Relief, Best Laxatives for Constipation Fast Acting

7% OffFree Shipping

Fast relief when needed most.
Affordable quality and effectiveness.
Safety standards you can trust.

Main Highlights

Get Things Moving Smoothly Again ... When constipation threatens to ruin your day, Max Lax offers the temporary relief you need. Each maximum strength tablet is packed with sennosides 25mg. Take 2 tablets once or twice daily & stimulate your system.
Wake Up Ready to Go ... We formulated our laxatives for constipation relief for adults to offer overnight relief; so, you won't be crippled by bathroom anxiety. The sennosides laxative generally produces bowel movement in 6 to12 hours.
Impressive Results at a Fraction of the Cost ... Don't fall into the branding trap. Our stimulant laxative tablets have National Brand Equivalency. This means you get the same quality as products that are 2X as expensive. Be savvy. Shop smart. Save big.
Take Your Meds with Total Ease ... No more thinking twice before addressing the discomfort in your gut. With our stimulant laxative tablets, relief will be an intimidation-free affair.
Your Safety Comes First ... At Time Cap Labs, your wellbeing is our business. That's why we work hard to ensure our laxatives for constipation for women & men live up to the highest standards. Each bottle comes with a seal for a serving of safety.

Colon Cleanser Detox for Weight Flush - 15 Day Intestinal Cleanse Pills & Probiotic - Fast Natural Laxative for Constipation Relief - Bowel Movement Supplements for Stomach Bloating, Gut Loss Support

Colon Cleanser Detox for Weight Flush - 15 Day Intestinal Cleanse Pills & Probiotic - Fast Natural Laxative for Constipation Relief - Bowel Movement Supplements for Stomach Bloating, Gut Loss Support

Promotes healthy gut function.
Supports weight loss process.
Relieves constipation effectively.

Main Highlights

15 Day Colon Cleanse for Detox & Weight Flush: Flush bowel waste with this powerful intestinal colon cleanser; natural detox pills for constipation relief, stomach bloating, IBS & weight loss
Fast Digestive Cleanse & Probiotics: Our colon cleanser detox pills support digestion and a healthy gut with lactobacillus acidophilus, a strong probiotic for stomach bloating relief for men & women
Constipation Relief: Our aloe vera detox formula is an advanced herbal blend that promotes regular bowel movements and a detox cleanse; the laxatives & herbs help support a full colon cleanse detox
Prebiotic Support: Psyllium husk & flaxseed provide fiber to help regularity, natural bowel movement, a cleaner gut & enhance probiotics; feel your best with our colon cleanser detox for weight loss
Clean Out Waste: Flush toxins by cleansing with Dr. Bo 15 day colon cleanse laxative supplements; quick cleanse supplement pills for weight loss, energy & daily regular bowel movements for adults

GenCare - Maximum Strength Senna Laxative 25mg (100 Tablets) - Gentle Constipation Relief Sennosides USP Stimulant Laxatives Digestion Pills - Natural Overnight Relief while You Sleep - Generic Ex Lax

GenCare - Maximum Strength Senna Laxative 25mg (100 Tablets) - Gentle Constipation Relief Sennosides USP Stimulant Laxatives Digestion Pills - Natural Overnight Relief while You Sleep - Generic Ex Lax

23% OffFree Shipping

Gentle overnight relief guaranteed.
Natural ingredient for effective results.
Affordable alternative for everyday needs.

Main Highlights

MAXIMUM STRENGTH OVERNIGHT RELIEF – Formulated for dependable overnight relief from occasional constipation. This stimulant laxative helps restore regularity with a maximum-strength 25mg dose of sennosides.
SENNOSIDES 25MG LAXATIVE – Each tablet contains 25mg of sennosides, the active ingredient extracted from natural senna leaves. This natural laxative supports gentle but effective elimination without uncomfortable side effects.
NATURAL & FAST-ACTING – Senna-based natural laxatives for constipation are fast-acting, triggering the body’s natural intestinal processes to gently support a bowel movement without cramping. Best taken at bedtime.
GAS & BLOATING RELIEF - These laxatives are for women, men, teens and children as young as 6 to help reduce constipation symptoms such as visible and uncomfortable bloating, flatulence or gas that gets trapped in the body.
COMPARE TO EX-LEX – 100 count. GenCare Senna 25mg delivers the same active ingredient as Ex-Lex at a lower price. Keep relief close by when you need it with more tablets per bottle to help you stay prepared.

Colace 2-In-1 Stool Softener & Stimulant Laxative Tablets, Gentle Constipation Relief in 6-12 Hours, 30 Count

Colace 2-In-1 Stool Softener & Stimulant Laxative Tablets, Gentle Constipation Relief in 6-12 Hours, 30 Count

19% OffFree Shipping

Gentle, dependable relief from constipation.
Fast-acting within 6-12 hours.
Safe for everyday use.

Main Highlights

Relieve occasional constipation with Colace® 2-IN-1 Tablets
Docusate sodium, a stool softener, allows water and fats to get into the stool
Standardized senna concentrate is a laxative that helps to gently stimulate motility of the intestines
Gentle, dependable relief in 6-12 hours
Safe, gentle, and effective