10 Best Septic Tank Enzymes And Bacteria of 2025

Last updated on 07/23/2025
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1
9.8
Exceptional
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Septic Tank Treatment - 1 Year Supply of Septic Safe Dissolvable Easy Flush Live Bacteria Packets (12 Count) - Best Way to Prevent Expensive Sewage Backups - Made in USA
SEPTIC TREATMENT BY CABIN OBSESSION
Septic Tank Treatment - 1 Year Supply of Septic Safe Dissolvable Easy Flush Live Bacteria Packets (12 Count) - Best Way to Prevent Expensive Sewage Backups - Made in USA
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Why We Love It
  • Promotes a healthy septic system.
  • All-natural and environmentally friendly.
  • Eliminates odor for cleaner spaces.
Main Highlights
  • 🌿 YOU’RE JUST ONE FLUSH AWAY FROM A HEALTHY SEPTIC SYSTEM! Our monthly easy flush dissolving packets are specially formulated to help break down waste and maintain a properly functioning septic system. This is the easiest and most efficient way to prevent expensive septic tank backups and drain field repairs. Just flush one packet down your toilet each month!
  • 🌿 SCIENTIFICALLY SELECTED BACTERIA CULTURES. Each packet contains billions of active bacteria cultures that are scientifically selected to produce, activate, and recharge the enzymes needed to reduce solids and decompose the different types of waste found in both the sludge layer and scum layer of your septic tank, and even out into the leach field.
  • 🌿 ALL NATURAL, ENVIRONMENTALLY FRIENDLY, & MADE IN THE USA. Each flushable septic treatment packet is all natural, with no chemical additives. They’re safe for all home plumbing lines, any black water system or cesspool, and both aerobic and anaerobic septic systems, so flush each packet down your toilet with absolute confidence!
  • 🌿 ELIMINATES ODOR, AND GREAT FOR YOUR RV AND BOAT TOO. Not only is this the best way to maintain a healthy residential septic system, but our concentrated formula dissolvable enzyme pouches are also ideal for use in marine holding tanks and camper toilets too! And because of the advanced digestion rate of odor causing bio organic wastes, they aid in controlling and getting rid of bad smells too. Your nose will thank you!
  • 🌿 PREVENTS EXPENSIVE SEPTIC BACKUPS AND REPAIRS. A small investment in our septic tank treatments help to prevent clogs and bulky buildup that causes septic overflow. The billions of bacteria in each packet digest solid waste, converting it to liquid, preventing costly repairs and frequent pumping.
9.8
Exceptional
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2
9.7
Exceptional
Save 36%
Septic Tank System Treatment Pods - 12 Dissolving Packets | Enzyme-Producing Live Bacteria Solution | 1 Year Supply Professional Eco-Friendly Maintenance | Prevent Clogs, Odor & Backups | Made in USA
ACTIVE
Septic Tank System Treatment Pods - 12 Dissolving Packets | Enzyme-Producing Live Bacteria Solution | 1 Year Supply Professional Eco-Friendly Maintenance | Prevent Clogs, Odor & Backups | Made in USA
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Why We Love It
  • Effortless septic system maintenance.
  • Natural bacteria promote long-term health.
  • Compatible with various septic systems.
Main Highlights
  • Effortless Monthly Maintenance: Keep Your Septic System Healthy with Our Simple Flushable Additive. Just Flush One Packet Down the Toilet for Easy Septic Defense.
  • Natural Live Bacteria: Each Pak Contains a Bio Starter Blend of Billions of CFU Which Produce Helper Enzymes for your Sewer Tank. Compare to Yeast, Chemicals, Cleaner, or Odor Neutralizer that Cover up Long Term Issues in Your Ceptic Tank, Drain Field and Cesspool. ACTIVE is Professionally Formulated & Made in USA.
  • Wide Septic Compatibility: ACTIVE Works in Conventional & Chamber Systems, Drip Distribution System, Both Aerobic and Anaerobic Treatment Units, Rv Holding Tanks, and Black Tanks
  • Full System Clog Eliminator: Save Yourself from Expensive Repairs with our Industrial Strength Drainer & Deodorizer. ACTIVE Septic Treatment Prevents Unwanted Smell and Repair Balance of Beneficial Microbes
  • Best Value Maintenance: Entire Year Supply (12 Treatments) in Each Pack. Compare to Products With Pellets, Tablets, Cakes or Less Packs
9.7
Exceptional
Save 36%
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3
9.6
Superb
ccls Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-Toxic/Non-Hazardous/Non-Corrosive (4-Pack)
ccls
ccls Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-Toxic/Non-Hazardous/Non-Corrosive (4-Pack)
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Why We Love It
  • Naturally occurring, safe ingredients.
  • Odor-free and non-toxic.
  • Biodegradable with no harmful chemicals.
Main Highlights
  • How It Works: The bacteria present produce enzymes that break down organic solid materials into food for bacteria. The bacteria digest this material and use the food to multiply and produce enzymes. This cycle continues until the waste has been completely digested, leaving the area free of solids, free-flowing, and odor-free.
  • Chemical Free: Formulated from naturally occurring organisms. Non-toxic, non-hazardous, non-corrosive, non-combustible. It emits no odors or harmful fumes and will not harm humans, pets or irritate the skin.
  • Biodegradable: Contains no acids, caustics, chloride, or volatile organic compounds. Liquid is biodegradable, safe for environment, and completely safe to store and use in the home when used according to directions.
  • Septic Tank Systems and Cesspools: If systems are not properly maintained they will fill up with solids, they will clog the soil absorption areas, they will contaminate the soil, and they will become health hazards and burdensome expense.
  • Maintenance and Usage: Apply at least monthly in the home to maintain bacterial balance in the septic tank or cesspool. Older, overtaxed, or neglected systems may require a shock dosage to create high bacteria level.
9.6
Superb
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4
9.6
Superb
ccls Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-toxic/Non-Hazardous/Non-Corrosive (1-Gallon)
ccls
ccls Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-toxic/Non-Hazardous/Non-Corrosive (1-Gallon)
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Why We Love It
  • Chemical-free formulation for safety.
  • Effectively digests organic waste.
  • Biodegradable and environmentally friendly.
Main Highlights
  • How It Works: The bacteria present produce enzymes that break down organic solid materials into food for bacteria. The bacteria digest this material and use the food to multiply and produce enzymes. This cycle continues until the waste has been completely digested, leaving the area free of solids, free-flowing, and odor-free.
  • Chemical Free: Formulated from naturally occurring organisms. Non-toxic, non-hazardous, non-corrosive, non-combustible. It emits no odors or harmful fumes and will not harm humans, pets or irritate the skin.
  • Biodegradable: Contains no acids, caustics, chloride, or volatile organic compounds. Liquid is biodegradable, safe for environment, and completely safe to store and use in the home when used according to directions.
  • Septic Tank Systems and Cesspools: If systems are not properly maintained they will fill up with solids, they will clog the soil absorption areas, they will contaminate the soil, and they will become health hazards and burdensome expense.
  • Maintenance and Usage: Apply at least monthly in the home to maintain bacterial balance in the septic tank or cesspool. Older, overtaxed, or neglected systems may require a shock dosage to create high bacteria level.
9.6
Superb
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5
9.5
Superb
Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.
Bio-Clean
Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.
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Why We Love It
  • Naturally digests organic waste.
  • Cost-effective and efficient solution.
  • Safe for the environment.
Main Highlights
  • LISTING IS FOR 1 TWO POUND CANISTER
  • Special combination of natural microbes and enzymes that DIGESTS dead organic waste found in your plumbing system
  • Eliminates costly backups. Up to 100 Drain Treatments.
  • Environmentally friendly and safe.
  • Multi Purpose. Kitchen sinks, showers, bath tubs, garbage disposals, septic tanks & fields, cat litter pans, motor homes and much more!
9.5
Superb
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6
9.3
Superb
CCLS Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-Toxic/Non-Hazardous/Non-Corrosive (1-Quart)
ccls
CCLS Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-Toxic/Non-Hazardous/Non-Corrosive (1-Quart)
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Why We Love It
  • Naturally derived, safe ingredients.
  • Odor-free and non-toxic formula.
  • Supports septic system health.
Main Highlights
  • How It Works: The bacteria present produce enzymes that break down organic solid materials into food for bacteria. The bacteria digest this material and use the food to multiply and produce enzymes. This cycle continues until the waste has been completely digested, leaving the area free of solids, free-flowing, and odor-free.
  • Chemical Free: Formulated from naturally occurring organisms. Non-toxic, non-hazardous, non-corrosive, non-combustible. It emits no odors or harmful fumes and will not harm humans, pets or irritate the skin.
  • Biodegradable: Contains no acids, caustics, chloride, or volatile organic compounds. Liquid is biodegradable, safe for environment, and completely safe to store and use in the home when used according to directions.
  • Septic Tank Systems and Cesspools: If systems are not properly maintained they will fill up with solids, they will clog the soil absorption areas, they will contaminate the soil, and they will become health hazards and burdensome expense.
  • Maintenance and Usage: Apply at least monthly in the home to maintain bacterial balance in the septic tank or cesspool. Older, overtaxed, or neglected systems may require a shock dosage to create high bacteria level.
9.3
Superb
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7
9.3
Superb
MICROBE-LIFT Septic Tank and Cesspool Treatment Enzymes - 6 Month Supply - Bacteria Digests Grease, Fats, Oils and Tissue, 32 Fl Oz (Pack of 2)
MICROBE-LIFT
MICROBE-LIFT Septic Tank and Cesspool Treatment Enzymes - 6 Month Supply - Bacteria Digests Grease, Fats, Oils and Tissue, 32 Fl Oz (Pack of 2)
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Why We Love It
  • Six-month supply in one bottle.
  • Reduces odors quickly and effectively.
  • All-natural ingredients, environmentally friendly.
Main Highlights
  • CONTAINS 6 MONTHS OF TREATMENT: Each 32oz bottle of the Microbe-Lift septic tank treatment contains 6 months of supply. Simply pour the entire bottle in your toilet and flush for preventive maintenance.
  • DRASTICALLY REDUCE SEPTIC SYSTEM AND TANK ODORS: The Microbe-Lift septic system treatment will produce a slight odor when first applying. This is due to the hydrogen sulfide which is naturally produced by the sulfate reducing bacteria in the product. The hydrogen sulfide provides an energy source for bacteria, which oxidizes hydrogen sulfide. A little odor is released upon application and is gone in minutes. No competitor on the market has a product as potent and fast working as Microbe-Lift's.
  • QUALITY INGREDIENTS AND ENVIRONMENTALLY SAFE: The Microbe-Lift Residential Septic System & Cesspool Treatment contains a special blend of our highly specialized microbial cultures. Healthy bacteria colonies are essential for the proper operation and maintenance of residential septic systems. That means our septic treatment is all-natural, contains zero chemicals, is non-toxic, non-pathogenic, and groundwater safe!
  • PREVENT COSTLY SEPTIC BACKUP AND REPAIRS: The Microbe-Lift septic tank treatment digests grease, fats, oils, and tissue that will improve your septic flow and keep your tank from overflowing and damaging your property!
  • DIRECTIONS FOR USE: For first time use, add the full 32oz bottle and flush. For troubled systems, add 64oz for the first application then 32oz every other week for the next 4 weeks. After that, system maintenance calls for adding 32oz every 6 months thereafter.
9.3
Superb
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8
9.2
Superb
Walex Bio-Active Home Septic Tank Treatment - Strong Digestive Power with Beneficial Bacteria & Enzymes for Liquefying Solids & Breaking Down Waste, Odor Neutralizer -1 Year Supply, 12 Packets
Walex
Walex Bio-Active Home Septic Tank Treatment - Strong Digestive Power with Beneficial Bacteria & Enzymes for Liquefying Solids & Breaking Down Waste, Odor Neutralizer -1 Year Supply, 12 Packets
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Why We Love It
  • Powerful enzymatic septic care.
  • One packet per month.
  • Plumbing and environment safe.
Main Highlights
  • POWERFUL DIGESTIVE POWER - Bio-Active Septic Tank Treatment contains beneficial septic enzymes that efficiently liquefy solids and tissue, providing commercial-strength septic tank care.
  • PORTION CONTROL - With just one Bio-Active septic tank cleaner packet per month, your septic system thrives. Billions of beneficial septic system enzymes ensure a smoothly running septic tank.
  • PLUMBING SAFE - Bio-Active septic tank pods tackle household waste buildup. Say goodbye to damage from household cleaners. Our septic packets offer safety for septic tanks and plumbing systems.
  • ODORS VANQUISHED - Bid farewell to inconvenient septic tank odors. Bio-Active's enzyme army prevents backups and overflows, the perfect sewage odor neutralizer. California compliant.
  • MADE IN USA - Walex has manufactured odor control and sanitation products since 1987. We are a family-run business that manufactures Bio-Active in our North Carolina facility.
9.2
Superb
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9
9.1
Superb
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Roebic K-37-Q Septic Tank Treatment: Removes Clogs, Environmentally Friendly Bacteria Enzymes, Safe for Toilets, 32 Fl Oz - Lasts 1 Year, 32 Ounces
Roebic
Roebic K-37-Q Septic Tank Treatment: Removes Clogs, Environmentally Friendly Bacteria Enzymes, Safe for Toilets, 32 Fl Oz - Lasts 1 Year, 32 Ounces
20% OffFree Shipping
Why We Love It
  • Safe for all plumbing materials.
  • Promotes efficient system operation.
  • Environmentally friendly and biodegradable.
Main Highlights
  • Safe for all plumbing, works in septic tanks and drain fields. Prevents clogging, odors, and overflowing receptacles
  • Restores natural balance, promotes rapid breakdown of solids, reduces sludge, scum levels, odors, and clogs for efficient system operation
  • Patented Roetech bacteria keeps system running smoothly, prevents common septic problems, and ensures efficient operation
  • Economical and easy to use. Treats a 500-gallon septic tank, lasting for a full year. Maintains system efficiency
  • Biodegradable, safe for the environment. Contains aerobic, spore-bearing bacteria resistant to soaps and detergents
9.1
Superb
Save 20%
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10
9.0
Superb
GREEN PIG Septic Tank Treatment Packets, Septic Safe Clog Remover, Prevents Expensive Septic Tank and Drain Field Failures, 4 Pods, 1-Year Supply
GREEN PIG
GREEN PIG Septic Tank Treatment Packets, Septic Safe Clog Remover, Prevents Expensive Septic Tank and Drain Field Failures, 4 Pods, 1-Year Supply
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Why We Love It
  • Prevents costly septic issues.
  • Eco-friendly and safe formula.
  • Easy drop-and-flush application.
Main Highlights
  • PREVENT EXPENSIVE CLOGS: Our septic tank treatment pods efficiently dissolve blockages, serving as septic tank enzymes and deodorizer to provide a healthy septic system
  • ENVIRONMENTALLY SAFE FORMULA: Septic treatment pods contain billions of bacteria and odor eliminator properties, working as a septic safe drain cleaner across your system
  • PROFESSIONAL STRENGTH ENZYMES: Powerful enzyme septic tank cleaner efficiently dissolves grease and fats, acting as a drain deodorizer for smell to maintain optimal tank performance
  • EASY-TO-USE, ODOR ELIMINATION: Drop and flush septic tank treatment pods to effectively function as a drain smell remover and offer hassle-free cleaning drain pipes solution
  • ECONOMICAL 1-YEAR SUPPLY: Green Pig septic tank treatment packets, used four times a year, act as accelerator drain field cleaner for tanks from 500 to 1500-gallons
9.0
Superb
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