10 Best Septic Tank Bio Enzymes of 2025

Last updated on 07/16/2025
Advertising disclosure
Best Choice
1
9.8
Exceptional
Save 14%
Septic Tank Treatment - 1 Year Supply of Septic Safe Dissolvable Easy Flush Live Bacteria Packets (12 Count) - Best Way to Prevent Expensive Sewage Backups - Made in USA
SEPTIC TREATMENT BY CABIN OBSESSION
Septic Tank Treatment - 1 Year Supply of Septic Safe Dissolvable Easy Flush Live Bacteria Packets (12 Count) - Best Way to Prevent Expensive Sewage Backups - Made in USA
14% OffFree Shipping
Why We Love It
  • Promotes a healthy septic system.
  • All-natural and environmentally friendly.
  • Eliminates odor for cleaner spaces.
Main Highlights
  • 🌿 YOU’RE JUST ONE FLUSH AWAY FROM A HEALTHY SEPTIC SYSTEM! Our monthly easy flush dissolving packets are specially formulated to help break down waste and maintain a properly functioning septic system. This is the easiest and most efficient way to prevent expensive septic tank backups and drain field repairs. Just flush one packet down your toilet each month!
  • 🌿 SCIENTIFICALLY SELECTED BACTERIA CULTURES. Each packet contains billions of active bacteria cultures that are scientifically selected to produce, activate, and recharge the enzymes needed to reduce solids and decompose the different types of waste found in both the sludge layer and scum layer of your septic tank, and even out into the leach field.
  • 🌿 ALL NATURAL, ENVIRONMENTALLY FRIENDLY, & MADE IN THE USA. Each flushable septic treatment packet is all natural, with no chemical additives. They’re safe for all home plumbing lines, any black water system or cesspool, and both aerobic and anaerobic septic systems, so flush each packet down your toilet with absolute confidence!
  • 🌿 ELIMINATES ODOR, AND GREAT FOR YOUR RV AND BOAT TOO. Not only is this the best way to maintain a healthy residential septic system, but our concentrated formula dissolvable enzyme pouches are also ideal for use in marine holding tanks and camper toilets too! And because of the advanced digestion rate of odor causing bio organic wastes, they aid in controlling and getting rid of bad smells too. Your nose will thank you!
  • 🌿 PREVENTS EXPENSIVE SEPTIC BACKUPS AND REPAIRS. A small investment in our septic tank treatments help to prevent clogs and bulky buildup that causes septic overflow. The billions of bacteria in each packet digest solid waste, converting it to liquid, preventing costly repairs and frequent pumping.
9.8
Exceptional
Save 14%
Amazon Logo
Best Value
2
9.6
Superb
Save 36%
Septic Tank System Treatment Pods - 12 Dissolving Packets | Enzyme-Producing Live Bacteria Solution | 1 Year Supply Professional Eco-Friendly Maintenance | Prevent Clogs, Odor & Backups | Made in USA
ACTIVE
Septic Tank System Treatment Pods - 12 Dissolving Packets | Enzyme-Producing Live Bacteria Solution | 1 Year Supply Professional Eco-Friendly Maintenance | Prevent Clogs, Odor & Backups | Made in USA
36% OffFree Shipping
Why We Love It
  • Effortless septic system maintenance.
  • Natural bacteria promote long-term health.
  • Compatible with various septic systems.
Main Highlights
  • Effortless Monthly Maintenance: Keep Your Septic System Healthy with Our Simple Flushable Additive. Just Flush One Packet Down the Toilet for Easy Septic Defense.
  • Natural Live Bacteria: Each Pak Contains a Bio Starter Blend of Billions of CFU Which Produce Helper Enzymes for your Sewer Tank. Compare to Yeast, Chemicals, Cleaner, or Odor Neutralizer that Cover up Long Term Issues in Your Ceptic Tank, Drain Field and Cesspool. ACTIVE is Professionally Formulated & Made in USA.
  • Wide Septic Compatibility: ACTIVE Works in Conventional & Chamber Systems, Drip Distribution System, Both Aerobic and Anaerobic Treatment Units, Rv Holding Tanks, and Black Tanks
  • Full System Clog Eliminator: Save Yourself from Expensive Repairs with our Industrial Strength Drainer & Deodorizer. ACTIVE Septic Treatment Prevents Unwanted Smell and Repair Balance of Beneficial Microbes
  • Best Value Maintenance: Entire Year Supply (12 Treatments) in Each Pack. Compare to Products With Pellets, Tablets, Cakes or Less Packs
9.6
Superb
Save 36%
Amazon Logo
3
9.6
Superb
Septic Tank Shock Treatment | Bio Enzyme Septic Safe |Clears Leach & Drain Fields, Dissolves Organic Solids, Grease, Hair - Drain Deodorizer (7.5 LBS)
Eco Strong
Septic Tank Shock Treatment | Bio Enzyme Septic Safe |Clears Leach & Drain Fields, Dissolves Organic Solids, Grease, Hair - Drain Deodorizer (7.5 LBS)
Free Shipping
Why We Love It
  • Restores septic flow naturally.
  • Saves money on repairs.
  • Eliminates odors and sludge.
Main Highlights
  • Septic Emergency Treatment: Restore septic flow to failing leach fields, drain fields, dry wells and cesspools without digging. This industrial strength bio-enzymatic formula naturally breaks down years of bio mat buildup in leach fields.
  • Prevents Costly Repairs: Septic Liberator uses trillions of bio-enzymes to chop up and digest organic build-up, increasing flow and soil absorption while supporting the system's balance.
  • Eliminate Odors, Wet Grass, and Digest Sludge: In addition to the bio mat, the Septic Liberator breaks down waste, paper, fats, oils, and grease, along with hair, in the septic tank and leach lines.
  • What To Expect: You can save thousands in repairs using Septic Liberator. However, biology takes time to work. Some systems may require multiple treatments over the span of several weeks to months to fully restore flow. It is normal for the powder to not dissolve when mixed with water prior to adding to the system.
  • Chemical Free: Trusted by the Pro’s, Septic Liberator's all-natural bio-enzymatic formula is safe for use in all types of plumbing, drains, septic systems, leach and drain fields, cesspools, and pits. Septic Liberator is proudly made in America.
9.6
Superb
Amazon Logo
4
9.4
Superb
Bio-Clean Ultimate Drain Cleaning Kit Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.
Bio-Clean
Bio-Clean Ultimate Drain Cleaning Kit Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.
Free Shipping
Why We Love It
  • Comprehensive drain maintenance solution.
  • Natural bacteria for effective cleaning.
  • Simple monthly treatment process.
Main Highlights
  • Complete Drain Care: Includes a 2lb jar of Bio-Clean, a mixing cup, reminder magnet, and a hair removal tool for comprehensive drain maintenance
  • Biological Action: Utilizes natural bacteria and enzymes to digest organic waste like grease, hair, and soap scum, keeping your drains clean and clog-free
  • Easy to Use: Simply mix 1/2 cup of Bio-Clean with 1 gallon of warm water, pour it down the drain, and let it sit for 30 minutes before rinsing
  • Regular Maintenance: Monthly treatments with Bio-Clean help prevent future drain issues, ensuring your plumbing system stays trouble-free
9.4
Superb
Amazon Logo
5
9.2
Superb
Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.
Bio-Clean
Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.
Free Shipping
Why We Love It
  • Naturally digests organic waste.
  • Cost-effective and efficient solution.
  • Safe for the environment.
Main Highlights
  • LISTING IS FOR 1 TWO POUND CANISTER
  • Special combination of natural microbes and enzymes that DIGESTS dead organic waste found in your plumbing system
  • Eliminates costly backups. Up to 100 Drain Treatments.
  • Environmentally friendly and safe.
  • Multi Purpose. Kitchen sinks, showers, bath tubs, garbage disposals, septic tanks & fields, cat litter pans, motor homes and much more!
9.2
Superb
Amazon Logo
6
9.0
Superb
Homey Aim Septic Tank Treatment. 1 Year Supply. Safe Green Cultures and Enzymes Powder in Packets Avoid Bad Odors, Organic Clogs and Expensive Sewage Backups.
Homey Aim
Homey Aim Septic Tank Treatment. 1 Year Supply. Safe Green Cultures and Enzymes Powder in Packets Avoid Bad Odors, Organic Clogs and Expensive Sewage Backups.
Free Shipping
Why We Love It
  • Prevents costly sewage backups.
  • Keeps your home fresh.
  • Eco-friendly and safe solution.
Main Highlights
  • Prevent Costly Sewage Backups: Protect your septic system from expensive repairs with our advanced Bio Aim septic tank treatment. The monthly packs use a potent blend of enzymes that dissolve organic clogs, preventing blockages and ensuring hassle-free plumbing. One 2 oz. pack contains 113 billion bacterial organisms. Use it year-round, especially before hosting events, family gatherings, or after heavy usage to prevent backups. (Package label may vary)
  • Keep Your Home Fresh and Odor-Free: Homey Aim Septic Tank Treatment Pods combat unpleasant odors, ensuring your home always smells clean and inviting. Our powerful enzyme powder works continuously to break down waste, keeping your septic system running smoothly year-round. It is specifically designed to work within the septic tank environment.
  • Simple and Convenient 12-Month Supply: Enjoy a full-year supply of septic tank care with twelve pre-measured monthly 2 oz. packs. Just drop one pod into the toilet each month for effortless maintenance. No mess, no fuss—just a reliable, easy septic tank treatment solution for maintaining your system health without frequent costly interventions. You get the biggest pods in the industry by weight. Enjoyed by homeowners, families, RV owners, and caretakers of cabins.
  • Eco-Friendly and Safe for Your Home: Homey Aim septic tank treatment pods are a sustainable choice for maintaining your septic system. Made with environmentally friendly enzymes, these dissolvable pods are safe for your family and kind to the planet, prioritizing both effectiveness and eco-friendliness. Ideal for eco-conscious families, property owners, and outdoor enthusiasts of any age.
  • Trusted Brand Quality: Homey Aim is committed to providing top-tier septic treatment solutions. Our enzyme powder is designed to outperform other brands, ensuring your septic system remains in optimal condition without frequent interventions. Use it as an alternative to traditional septic treatments and harsh chemical cleaners. This treatment can be complemented with routine plumbing maintenance and other septic-friendly cleaning products. It is made in the USA with the best quality ingredients. Backed by the manufacturer.
9.0
Superb
Amazon Logo
7
8.8
Excellent
BioWonder Septic Tank Treatment - Prevent Backups & Reduce Odor - 100% All-Natural Enzymes - Disposal, Drain, RV, Septic, Grease Trap, Toilet, Shower - 2lbs 60 Treatments
BioWonder
BioWonder Septic Tank Treatment - Prevent Backups & Reduce Odor - 100% All-Natural Enzymes - Disposal, Drain, RV, Septic, Grease Trap, Toilet, Shower - 2lbs 60 Treatments
Free Shipping
8.8
Excellent
Amazon Logo
8
8.7
Excellent
Bio-Tab for Septic Systems 8 oz (226.5g) 14 Tablets
Bio-Tab
Bio-Tab for Septic Systems 8 oz (226.5g) 14 Tablets
Free Shipping
8.7
Excellent
Amazon Logo
9
8.7
Excellent
ccls Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-toxic/Non-Hazardous/Non-Corrosive (1-Gallon)
ccls
ccls Septic Tank and Cesspool Treatment Additive/Organic Enzyme Producing Bacteria/Non-toxic/Non-Hazardous/Non-Corrosive (1-Gallon)
Free Shipping
Why We Love It
  • Chemical-free formulation for safety.
  • Effectively digests organic waste.
  • Biodegradable and environmentally friendly.
Main Highlights
  • How It Works: The bacteria present produce enzymes that break down organic solid materials into food for bacteria. The bacteria digest this material and use the food to multiply and produce enzymes. This cycle continues until the waste has been completely digested, leaving the area free of solids, free-flowing, and odor-free.
  • Chemical Free: Formulated from naturally occurring organisms. Non-toxic, non-hazardous, non-corrosive, non-combustible. It emits no odors or harmful fumes and will not harm humans, pets or irritate the skin.
  • Biodegradable: Contains no acids, caustics, chloride, or volatile organic compounds. Liquid is biodegradable, safe for environment, and completely safe to store and use in the home when used according to directions.
  • Septic Tank Systems and Cesspools: If systems are not properly maintained they will fill up with solids, they will clog the soil absorption areas, they will contaminate the soil, and they will become health hazards and burdensome expense.
  • Maintenance and Usage: Apply at least monthly in the home to maintain bacterial balance in the septic tank or cesspool. Older, overtaxed, or neglected systems may require a shock dosage to create high bacteria level.
8.7
Excellent
Amazon Logo
10
8.7
Excellent
Septic Drain and Leach Field Treatment | Bio-Enzyme Cleaner Breaks Down and Digest Clogs | Removes Odors & Mainline Cleaner (64 OZ)
Eco Strong
Septic Drain and Leach Field Treatment | Bio-Enzyme Cleaner Breaks Down and Digest Clogs | Removes Odors & Mainline Cleaner (64 OZ)
Free Shipping
Why We Love It
  • Cleans and rebalances septic systems.
  • Eliminates unpleasant sewage odors.
  • Speeds up slow draining process.
Main Highlights
  • Cleans, Clears, and Rebalances: Leach and Drain Field Blast is a bio-enzymatic septic treatment designed to tune up sluggish and smelly systems. This avoids future costly repairs as it will extend the lifespan of your leach field.
  • Eliminate Sewage Odors: Erase and prevent foul odors in your bathroom and yard with this easy to use treatment. Simply pour it down the toilet and flush while the bio-enzymes break down organic build up in the septic tank and leach field.
  • Speed Up Slow Draining: Improve flow through your drain field speeding up draining inside your home. It will breakup paper, fats, oils, and grease along with hair
  • A Trusted Solution: Made in America and safe for use in all types of plumbing, drains, septic systems, leach and drain fields, cesspools, and pits.
  • NOTE: Use Eco Strong’s Septic Liberator for systems in later stages of failure. These symptoms include wet grass, increased septic tank pump out frequency and back ups.
8.7
Excellent
Amazon Logo