10 Best Nano Hydroxyapatite Toothpaste With Fluoride of 2025

Last updated on 07/16/2025

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Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Remineralizing, Natural, Sensitive Teeth, SLS Free, Xylitol Nano-Hydroxyapatite Toothpaste for Adults, Mint 4oz (USA Made)

Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Remineralizing, Natural, Sensitive Teeth, SLS Free, Xylitol Nano-Hydroxyapatite Toothpaste for Adults, Mint 4oz (USA Made)

NASA-inspired enamel repair technology.
Clinically proven 10% effectiveness.
Fluoride-free and safe for everyone.

Main Highlights

NASA-INSPIRED ENAMEL REPAIR: Developed from NASA's space research, our 10% Nano Hydroxyapatite toothpaste restores and strengthens enamel, better than fluoride, without the harmful side effects. Achieve next-level protection and care for your teeth with every brush.
CLINICALLY PROVEN 10% NANO HYDROXYAPATITE: Unlike other brands that hide their Nano-Hydroxyapatite percentages, our toothpaste contains the full 10% Nano Hydroxyapatite—the clinically proven amount required for effective enamel restoration. Our nano-sized particles are precisely engineered to fill the microscopic pores in your teeth, delivering superior remineralization and protection.
NATURAL WHITENING, NO SENSITIVITY: Say goodbye to harsh bleaching agents. Our nano hydroxyapatite toothpaste smooths and whitens teeth by filling micro-lesions in the enamel, leaving you with a glossier, brighter smile—without causing sensitivity.
FLUORIDE FREE & SAFE FOR ALL AGES: Our toothpaste is completely fluoride-free, offering a safe alternative for those looking to avoid the negative health impacts of fluoride. Our nHa toothpaste is made with biocompatible ingredients, safe if swallowed and recommended by dentists nation-wide.
MADE IN USA WITH CLEAN, NATURAL INGREDIENTS: Made in the USA with premium, natural ingredients. Our toothpaste is fluoride-free, SLS-free, with birch xylitol to promote oral health. No artificial colors or flavors—just clean, gentle care for your mouth.

SuperMouth Fluoride Toothpaste - Adults & Kids, Fights Cavities, Whitens, Nano Hydroxyapatite, Dentist Developed, Safe Clean Ingredients, Gentle on Sensitive Teeth, Vitamins D3 & K2, 4 Tasty Flavors

SuperMouth Fluoride Toothpaste - Adults & Kids, Fights Cavities, Whitens, Nano Hydroxyapatite, Dentist Developed, Safe Clean Ingredients, Gentle on Sensitive Teeth, Vitamins D3 & K2, 4 Tasty Flavors

Powerful cavity protection formula.
Gentle for sensitive teeth.
Delicious flavors for enjoyable brushing.

Main Highlights

Dual Power of Fluoride & Liquid Enamel Technology️ for Maximum Protection: Pair the cavity-fighting benefits of fluoride with our patented Liquid Enamel Technology️—a proprietary blend of 10%+ nano-hydroxyapatite, vitamins D3 & K2, and an alkaline pH—to help strengthen enamel, ease sensitivity, support gum health, and protect against cavities. Designed with optimal ingredient concentrations for maximum efficacy, it’s a powerful choice for both adults and kids.
Perfect for Sensitive Teeth & Microbiome Support: Our low Relative Dentin Abrasivity (RDA) of 67 and alkaline pH mean gentle yet effective cleaning, making it an ideal choice for those with sensitive teeth. Free from potent essential oils that can disturb the mouth’s natural balance, SuperMouth supports your oral microbiome while promoting a calmer, healthier environment for teeth and gums.
Delicious Flavors that Make Brushing Enjoyable: Turn daily brushing into a treat with four family-favorite flavors—Smooth Vanilla, Creamy Strawberry, Decadent Chocolate, and Fresh Mint. Our specially formulated spearmint avoids the burning sensation or aftertaste often linked to peppermint oils, delivering a refreshing but gentle experience that encourages consistent brushing for kids and adults alike.
Whitens Teeth for a Radiant Smile: Helps minimize surface stains and reveals a brighter smile thanks to the combined action of fluoride and nano-hydroxyapatite. Formulated with xylitol and prebiotics, this forward-thinking approach supports overall mouth health by promoting enamel integrity, helping you maintain confidence in every grin.
Clean, Expertly Developed, & Sustainably Packaged: Rely on a toothpaste free from artificial flavors, colors, sweeteners, SLS, titanium dioxide, and other potentially harsh additives. Dentist-developed and made in the USA with globally sourced premium ingredients, SuperMouth is vegan, gluten-free, and packaged with sustainable materials—so you can protect your teeth, gums, and the planet every time you brush.

Dr. Jen Super Paste/Toothpaste with Fluoride +10% Nano-Hydroxyapatite Travel Toothpaste for Teeth Whitening & Sensitive Teeth Care (3.4 Ounce (Pack of 1), Cool Mint)

Dr. Jen Super Paste/Toothpaste with Fluoride +10% Nano-Hydroxyapatite Travel Toothpaste for Teeth Whitening & Sensitive Teeth Care (3.4 Ounce (Pack of 1), Cool Mint)

Clinically proven for effective results.
Deep repair for long-lasting health.
Optimal mineral uptake for defense.

Main Highlights

Clinically Proven 10% Nano-Hydroxyapatite — The Gold Standard for Maximum Mineral uptake. Formulated with the optimal 10% concentration of nano-Hydroxyapatite, shown to deliver the highest levels of calcium and phosphate uptake into enamel for unmatched cavity defense and enamel repair.
Premium-Grade Nano-Hydroxyapatite for Deep Repair Below the Surface. Our ultra-fine, medical-grade nano-Hydroxyapatite penetrates deep into enamel and dentin micro-channels, restoring mineral content where decay starts—beneath the surface.

Dr. Jen's 10% Nano Hydroxyapatite Toothpaste - Fluoride Free, Xylitol Toothpaste (4oz, Cool Mint)

Dr. Jen's 10% Nano Hydroxyapatite Toothpaste - Fluoride Free, Xylitol Toothpaste (4oz, Cool Mint)

Clinically proven for effective repair.
Deep penetration for lasting protection.
Optimal mineral uptake for strong enamel.

Main Highlights

Clinically Proven 10% Nano-Hydroxyapatite — The Gold Standard for Maximum Mineral uptake. Formulated with the optimal 10% concentration of nano-Hydroxyapatite, shown to deliver the highest levels of calcium and phosphate uptake into enamel for unmatched cavity defense and enamel repair.
Premium-Grade Nano-Hydroxyapatite for Deep Repair Below the Surface. Our ultra-fine, medical-grade nano-Hydroxyapatite penetrates deep into enamel and dentin micro-channels, restoring mineral content where decay starts—beneath the surface.

CariFree Gel 1100 (Mint) Anti-Cavity Fluoride Toothpaste with Nano Hydroxyapatite, Cavity Prevention and Enamel Protection, Dentist Recommended for Kids and Adults, 2.40 oz.

CariFree Gel 1100 (Mint) Anti-Cavity Fluoride Toothpaste with Nano Hydroxyapatite, Cavity Prevention and Enamel Protection, Dentist Recommended for Kids and Adults, 2.40 oz.

Dentist-recommended for cavity prevention.
Real mint flavor for fresh taste.
Proudly made in the USA.

Main Highlights

Dentist-Recommended Fluoride Toothpaste: CariFree Fluoride Gel is recommended by dentists to help prevent cavities and promote good dental health. Fluoride is a key ingredient that strengthens tooth enamel and helps protect against decay. By using this toothpaste regularly, you can give your teeth an added layer of protection against cavities.
Real Mint Flavor: CariFree uses genuine mint oil to create a real, fresh taste that is safe to use every day. Our Gel is also made with xylitol, a naturally occurring, sweet-tasting ingredient found in many types of plants that research shows may reduce your risk of dental cavities.
Nano Hydroxyapatite: CariFree Gel 1100 contains nanoXIM by FlUIDINOVA, the highest quality nano hydroxyapatite that's the same shape and size as the naturally occurring hydroxyapatite found in saliva. Our toothpaste is a low-abrasion tooth gel that combines proven anti-cavity benefits, including .24% fluoride, nano hydroxyapatite and our unique, patented pH+ technology to neutralize acids—recommended for ages 3+
Fight Cavities and Promote Fresh Breath: CariFree Gel 1100 contains 0.24% sodium fluoride to fight cavities and help prevent tooth decay while also freshening your breath. With patented pH+ technology, CariFree toothpaste is designed to target the root cause of cavities while also leaving your breath minty fresh.
Proudly Made in the USA: CariFree products are meticulously formulated and produced in the USA, showcasing our commitment to domestic quality and local craftsmanship. Founded in Albany, Oregon, CariFree is committed to offering affordable, science-based solutions to common dental health concerns for the whole family.

NOBS (No Bad Stuff) Toothpaste Tablets - Nano Hydroxyapatite, Fluoride & Plastic Free, Eco & Travel Friendly - Remineralize with NHA (1 Month)

NOBS (No Bad Stuff) Toothpaste Tablets - Nano Hydroxyapatite, Fluoride & Plastic Free, Eco & Travel Friendly - Remineralize with NHA (1 Month)

Himalaya Botanique Whitening + Extra Strength Hydroxyapatite Toothpaste - 10% Nano Hydroxyapatite to Support Remineralization & Restore Enamel to Strengthen Teeth - Vegan, Mint Flavor, 3 oz

Himalaya Botanique Whitening + Extra Strength Hydroxyapatite Toothpaste - 10% Nano Hydroxyapatite to Support Remineralization & Restore Enamel to Strengthen Teeth - Vegan, Mint Flavor, 3 oz

Powerful whitening without bleach.
Extra strength for better results.
Natural ingredients for healthy teeth.

Main Highlights

Remineralizes & repairs enamel: Our nano hydroxyapatite toothpaste is formulated with the mineral form of calcium that is the primary component of tooth enamel, aiding the remineralization process and rebuilding the enamel structure for a winning smile
10% nano hydroxyapatite (nHA): This premium Himalaya toothpaste is crafted with an extra-strength 10% concentration of nano hydroxyapatite to strengthen enamel and support healthier-looking more resilient teeth
Great for sensitive teeth: Nano hydroxyapatite works by integrating with the enamel, making it gentle and non-abrasive while other ingredients help with whitening teeth
Herbal teeth whitening toothpaste: Fruit enzymes from Papaya and Pineapple work hard to remove surface stains to give you whiter teeth, while Neem and Pomegranate keep your whole mouth clean for a sparkling smile
Thoughtfully crafted: This fluoride free toothpaste is formulated without sodium lauryl sulfate (SLS), triclosan, parabens, or carrageenan; an ideal vegan and gluten free tooth paste

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured

19% OffFree Shipping

Promotes gum health effectively.
Whitens teeth while cleaning.
Safe for the whole family.

Main Highlights

APPROPRIATE FOR GUM HEALTH & ENAMEL REPAIR: A powerhouse next generation formula for gum health by harnessing the strength of Nano Hydroxyapatite (NHA)!
REMINERALIZES & WHITENS TEETH: Thanks to its innovative formula with Nano Hydroxyapatite (NHA), our toothpaste not only effectively cleans your teeth but also aids in the remineralization process. As a result, it improves your overall tooth enamel health and helps to brighten those pearly whites
BIOCOMPATIBLE: Free from Fluoride, Sulfates, Parabens & Artificial Flavors & Colors - we meticulously crafted our product to be 100% biocompatible, ensuring it’s safe for daily use and non-toxic when used as directed. A perfect way to take your oral hygiene routine to the next level!
APPROPRIATE FOR SENSITIVE TEETH: Gentle yet effective, it provides a soothing and refreshing experience for the whole family. Embrace an oral care routine designed for a luxurious experience
TASTE THE ELA MINT FUSION: A delightful fusion of refreshing mint, antioxidant-rich green tea, with a hint of cardamom. The invigorating mint leaves your breath feeling fresh & revitalized, with just a touch of cardamom adding a unique, yet welcome twist to your brushing experience. Say goodbye to the bland & mundane - say hello to a toothpaste flavor that excites your taste buds every time you brush

Hydroxyapatite Toothpaste for Advanced Enamel Protection & Tooth Strengthening, Fluoride-Free Fluoride-Free Formula with Gentle Mint, Fresh Breath, Reduce Tooth Sensitivity 2pcs

Hydroxyapatite Toothpaste for Advanced Enamel Protection & Tooth Strengthening, Fluoride-Free Fluoride-Free Formula with Gentle Mint, Fresh Breath, Reduce Tooth Sensitivity 2pcs

Restores and strengthens enamel.
Soothes sensitive teeth comfortably.
Delivers long-lasting fresh breath.

Main Highlights

【Advanced Enamel Protection】:This toothpaste Powered by hydroxyapatite, a naturally occurring mineral that helps effectively restore and strengthen tooth enamel, , reducing the risk of cavities and erosion, Maintaining oral health for a long time
【Dentist-Recommended Enamel Repair】: Hydroxyapatite toothpaste, containing 7.5% hydroxyapatite, can repair and remineralize fragile enamel, reducing daily wear and the risk of tooth decay. Clinically proven efficacy, relying on the natural repair properties of hydroxyapatite, can promote long-term oral resilience.
【Gentle for Sensitive Teeth】: Formulated with ‌pH-neutral hydroxyapatite‌ and a ‌100% fluoride-free formula‌, this toothpaste instantly soothes sensitive nerves while providing a deep yet non-abrasive clean. It strengthens enamel, prevents irritation, and eliminates discomfort during brushing—Perfect for everyday use on sensitive teeth.
【Natural Mint for Fresh Breath】: By neutralizing harmful oral bacteria and smoothing microscopic enamel cracks, our hydroxyapatite technology tackles the root causes of bad breath. Contains natural mint ingredients to ensure 12 hours of fresh breath, bringing a refreshing and clean experience, Enjoy ‌long-lasting freshness‌ without harsh chemicals, as it actively reduces plaque buildup and maintains a balanced oral microbiome.
【‌Daily Oral Care】: Nano Hydroxyapatite toothpaste Reduces tooth sensitivity in 2-5 days by sealing exposed dentin tubules, Gradually removes surface stains over 2-4 weeks while repairing micro-cracks in enamel within 4-8 weeks‌. Brush twice daily for 2 minutes Hydroxyapatite forms a mineral shield stronger than fluoride, To maximize the adhesion of hydroxyapatite. Pair with hydroxyapatite mouthwash for accelerated enamel regeneration‌.

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Orange Cream Flavor, 4oz 1Pk - US Manufactured

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Orange Cream Flavor, 4oz 1Pk - US Manufactured

19% OffFree Shipping

Powerful gum health support.
Whitening and remineralizing power.
Delightful citrus flavor experience.

Main Highlights

APPROPRIATE FOR GUM HEALTH & ENAMEL REPAIR: A powerhouse next generation formula for gum health by harnessing the strength of Nano Hydroxyapatite (NHA)!
REMINERALIZES & WHITENS TEETH: Thanks to its innovative formula with Nano Hydroxyapatite (NHA), our toothpaste not only effectively cleans your teeth but also aids in the remineralization process. As a result, it improves your overall tooth enamel health and helps to brighten those pearly whites
BIOCOMPATIBLE: Free from Fluoride, Sulfates, Parabens & Artificial Flavors & Colors - we meticulously crafted our product to be 100% biocompatible, ensuring it’s safe for daily use and non-toxic when used as directed. A perfect way to take your oral hygiene routine to the next level!
APPROPRIATE FOR SENSITIVE TEETH: Gentle yet effective, it provides a soothing and refreshing experience for the whole family. Embrace an oral care routine designed for a luxurious experience
CITRUS ZEST DELIGHT: Immerse yourself in the lively fusion of zesty oranges and creamy, natural vanilla. The vibrant citrus burst leaves your breath feeling invigorated, while the smooth vanilla adds a touch of indulgence to your brushing routine. Say farewell to the mundane and savor a toothpaste flavor that brings excitement to every brush.