10 Best Fluoride Free Hydroxyapatite Toothpaste Made In Usa of 2025

Last updated on 23/06/2025

Advertising disclosure

Terra & Co. Gentle Green Hydroxyapatite Toothpaste for Sensitive Teeth – USA-Made - Remineralizing Toothpaste with Vitamin B12 – Fluoride-Free, Vegan, SLS-Free – Mint, 3.4 oz

Terra & Co. Gentle Green Hydroxyapatite Toothpaste for Sensitive Teeth – USA-Made - Remineralizing Toothpaste with Vitamin B12 – Fluoride-Free, Vegan, SLS-Free – Mint, 3.4 oz

19% OffFree Shipping

Natural remineralization for strong enamel.
Gentle formula for sensitive teeth.
Effective ingredients for daily care.

Main Highlights

High Potency Hydroxyapatite: Terra & Co.'s enamel repair toothpaste is made with biocompatible minerals for the prevention of micro-cavities. Naturally occurring minerals make up 97% of your tooth enamel and 60% of your bones. Why is this so important? As your teeth recognize this natural component, it's easier for them to intake hydroxyapatite and remineralize lost minerals while filling microscopic 'holes'.
Safe and Gentle Formula: Gentle Green is an advanced low-abrasion toothpaste that has been third-party tested and is backed by science to help reduce tooth sensitivity and promote natural whitening without harsh chemicals. This non-toxic, plant-based formula gently cleans your teeth while protecting enamel.
Clean, Effective Ingredients: Our tooth remineralization and whitening toothpaste is a natural blend of high potency hydroxyapatite, xylitol, peppermint, wintergreen, and spearmint; It's made in the USA without fluoride, SLS, triclosan, parabens, artificial colors, or fragrances.
Suitable for the Most Sensitive Smiles: This natural toothpaste does not cause sensitivity or irritate the gums; Powered with low abrasive hydroxyapatite and xylitol, the perfect duo of enamel friendliness and oral microbiome support for long-term tooth and gum health that your dentist will notice.
Behind the Brush: While dentists focus on treating disease, Terra & Co. is dedicated to supporting your daily oral care routine with gentle, effective products. Our formulas are crafted to help maintain a healthy mouth, support a balanced oral microbiome, and encourage overall wellness. Beyond oral care, Terra & Co. provides essential oral care products to underserved and unhoused women and kids in our community.

Made by Dentists Professional Enamel Rebuilding Toothpaste - 2 Pack - Remineralizing Nano Hydroxyapatite Toothpaste with Sodium Fluoride, ADA Approved, Vegan, 2 x 4.2oz

Made by Dentists

Made by Dentists Professional Enamel Rebuilding Toothpaste - 2 Pack - Remineralizing Nano Hydroxyapatite Toothpaste with Sodium Fluoride, ADA Approved, Vegan, 2 x 4.2oz

Advanced enamel rebuilding technology.
Effective relief from tooth sensitivity.
Vegan and eco-friendly formula.

Main Highlights

Advanced Enamel Rebuilding: This hydroxyapatite toothpaste contains nano hydroxyapatite and fluoride to replenish and remineralize enamel, making teeth stronger and harder.
How It Works: Utilizes nano-sized Hydroxyapatite particles that penetrate deeply into the tooth to remineralize from within, restoring the natural strength of enamel.
Protects Against Sensitivity: This remineralizing toothpaste contains potassium nitrate to block sensitive pathways in your teeth, providing relief from discomfort while strengthening enamel.
ADA Approved: Officially recognized by the American Dental Association for its effectiveness in enamel restoration and cavity prevention.
Vegan, Cruelty-Free, & Eco-Friendly: A vegan-friendly formula that's also cruelty-free, with packaging made from 100% recyclable materials.

Zero Premium Toothpaste by Something Nice – Dentist Recommended Mint-Flavored Toothpaste with 10% Nano Hydroxyapatite, Fluoride-Free, SLS-Free, Enamel Repair for Adults & Kids Oral Care, Made in USA

Zero Premium Toothpaste by Something Nice – Dentist Recommended Mint-Flavored Toothpaste with 10% Nano Hydroxyapatite, Fluoride-Free, SLS-Free, Enamel Repair for Adults & Kids Oral Care, Made in USA

Enamel repair for healthier smiles.
Safe for the whole family.
Refreshing minty taste after use.

Main Highlights

FLUORIDE-FREE TOOTHPASTE with 10% Nano HYDROXYAPATITE: This advanced toothpaste effectively whitens teeth while using 10% Nano hydroxyapatite to repair and strengthen enamel, promoting a bright and healthy smile.
SLS-FREE TOOTHPASTE & SAFE FORMULA: Free from fluoride, sulfates, and harmful chemicals, this toothpaste is SLS-free and safe for daily use by both adults and kids, making it an ideal choice for family oral care.
ENAMEL REPAIR & SENSITIVE TEETH SOLUTION: Specially designed to support enamel remineralization, this toothpaste gently cleans while being perfect for those with sensitive teeth, ensuring a comfortable brushing experience.
REFRESHING MINT FLAVOR: Enjoy a delightful minty taste with our mint-flavored toothpaste, delivering a refreshing and invigorating feel after every use.
DENTIST RECOMMENDED & MADE IN THE USA: Proudly crafted in the USA, this premium toothpaste is dentist-recommended and trusted for effective oral care, suitable for both adults and kids.

RiseWell Mineral Toothpaste - All Natural Toothpaste with Hydroxyapatite - Made in The USA, No Added Fluoride, SLS-Free - for a Stronger and Healthier Teeth, Wild Mint, 3.4 Oz

RiseWell Mineral Toothpaste - All Natural Toothpaste with Hydroxyapatite - Made in The USA, No Added Fluoride, SLS-Free - for a Stronger and Healthier Teeth, Wild Mint, 3.4 Oz

Natural enamel strengthening formula.
Sensitive teeth relief guaranteed.
Travel-friendly and clean ingredients.

Main Highlights

REMINERALIZE AND SHINE WITH EVERY BRUSH: Our SLS free toothpaste with no added fluoride has Hydroxyapatite that strengthens enamel, naturally whitens teeth without harsh abrasives, and helps remineralize teeth. This natural sensitive toothpaste reduces sensitivity while delivering effective remineralization.
SENSITIVE TEETH RELIEF: Experience natural protection with our clean toothpaste for sensitive teeth! Unlike other toothpastes, this hydroxyapatite toothpaste uses hydroxyapatite to reduce sensitivity while remineralizing tooth enamel. For a stronger and healthier smile, try our hydroxyapatite-toothpaste.
100% CLEAN & TRAVEL-READY: This travel toothpaste is TSA-approved at 3.4 oz toothpaste, making it easy to take anywhere. Formulated to remineralize teeth, this no added fluoride toothpaste is free from sulfates, parabens, and artificial additives—pure, safe, and always ready remineralize toothpaste for your next trip!
LONG-LASTING NATURAL DENTIST TOOTHPASTE: This 3.4oz tube of remineralizing toothpaste with hydroxyapatite lasts approximately 3 months when used twice daily, a good toothpaste that provides continuous oral care without running out. Try RiseWell's hydroxyapatite whitening toothpaste!
MADE IN THE USA MINERAL TOOTHPASTE: RiseWell's hydroxyapatite whitening toothpaste is proudly manufactured in the USA. This natural whitening toothpaste is cruelty-free, vegan, and gluten free toothpaste. This made by dentist toothpaste offers a clean, ethical option for those who care about what goes into their oral health routine.

RiseWell Mineral Unflavored Toothpaste - Hydroxyapatite Flavorless Toothpaste - Made in The USA, Sensitive Teeth Whitening, No Added Fluoride, SLS-Free - Made by Dentists, 3.4 Oz

RiseWell Mineral Unflavored Toothpaste - Hydroxyapatite Flavorless Toothpaste - Made in The USA, Sensitive Teeth Whitening, No Added Fluoride, SLS-Free - Made by Dentists, 3.4 Oz

Natural ingredients for sensitive teeth.
Gentle remineralization for enamel strength.
Ethical, cruelty-free oral care choice.

Main Highlights

NATURAL INGREDIENTS, NO FLAVOR ADDED: Unflavored toothpaste for those sensitive to taste! Our Mineral Toothpaste gently cleans without artificial sweeteners, essential oils, or flavors. This sensitive toothpaste for sensitive teeth offers a neutral, no flavor toothpaste experience—a gentle, effective hydroxyapatite toothpaste option.
REMINERALIZE AND SHINE WITH EVERY BRUSH: This flavorless clean toothpaste is powered by hydroxyapatite to strengthen enamel and restore minerals. Our sensitive whitening toothpaste gently whitens without harsh abrasives. This natural remineralizing toothpaste also reduces sensitivity while effectively remineralizing your teeth.
SENSITIVE TEETH RELIEF: Enjoy gentle care with our flavorless natural toothpaste! Our non-SLS with xylitol toothpaste reduces sensitivity and strengthens enamel without any flavors. This natural sensitive toothpaste offers effective relief with a clean, neutral experience. Our non mint toothpaste is great for mint free toothpaste needs.
100% CLEAN & SAFE: Experience the clean protection made with natural ingredients you can trust! This no added fluoride toothpaste is a toothpaste with no sls, propylene glycol, artificial flavors, dyes, or Teflon. Our flavor free toothpaste gently cares for sensitive teeth with safe, effective protection.
MADE IN THE USA: RiseWell flavorless toothpaste for adults strengthens enamel and whitens naturally. This toothpaste without mint flavor is proudly made in the USA, gluten-free, vegan, cruelty-free, and sls-free toothpaste—offering a clean, ethical choice for your oral health routine.

Hydroxyapatite Toothpaste for Advanced Enamel Protection & Tooth Strengthening, Fluoride-Free Fluoride-Free Formula with Gentle Mint, Fresh Breath, Reduce Tooth Sensitivity 2pcs

Hydroxyapatite Toothpaste for Advanced Enamel Protection & Tooth Strengthening, Fluoride-Free Fluoride-Free Formula with Gentle Mint, Fresh Breath, Reduce Tooth Sensitivity 2pcs

Restores and strengthens enamel.
Soothes sensitive teeth comfortably.
Delivers long-lasting fresh breath.

Main Highlights

【Advanced Enamel Protection】:This toothpaste Powered by hydroxyapatite, a naturally occurring mineral that helps effectively restore and strengthen tooth enamel, , reducing the risk of cavities and erosion, Maintaining oral health for a long time
【Dentist-Recommended Enamel Repair】: Hydroxyapatite toothpaste, containing 7.5% hydroxyapatite, can repair and remineralize fragile enamel, reducing daily wear and the risk of tooth decay. Clinically proven efficacy, relying on the natural repair properties of hydroxyapatite, can promote long-term oral resilience.
【Gentle for Sensitive Teeth】: Formulated with ‌pH-neutral hydroxyapatite‌ and a ‌100% fluoride-free formula‌, this toothpaste instantly soothes sensitive nerves while providing a deep yet non-abrasive clean. It strengthens enamel, prevents irritation, and eliminates discomfort during brushing—Perfect for everyday use on sensitive teeth.
【Natural Mint for Fresh Breath】: By neutralizing harmful oral bacteria and smoothing microscopic enamel cracks, our hydroxyapatite technology tackles the root causes of bad breath. Contains natural mint ingredients to ensure 12 hours of fresh breath, bringing a refreshing and clean experience, Enjoy ‌long-lasting freshness‌ without harsh chemicals, as it actively reduces plaque buildup and maintains a balanced oral microbiome.
【‌Daily Oral Care】: Nano Hydroxyapatite toothpaste Reduces tooth sensitivity in 2-5 days by sealing exposed dentin tubules, Gradually removes surface stains over 2-4 weeks while repairing micro-cracks in enamel within 4-8 weeks‌. Brush twice daily for 2 minutes Hydroxyapatite forms a mineral shield stronger than fluoride, To maximize the adhesion of hydroxyapatite. Pair with hydroxyapatite mouthwash for accelerated enamel regeneration‌.

XyloBurst Hydroxyapatite Toothpaste with Xylitol - Fluoride-Free Hydroxyapatite Toothpaste, SLS-Free, Paraben Free, Cruelty Free, Made in The USA, Cool Mint, 4 oz Tube (3 Tubes)

XyloBurst Hydroxyapatite Toothpaste with Xylitol - Fluoride-Free Hydroxyapatite Toothpaste, SLS-Free, Paraben Free, Cruelty Free, Made in The USA, Cool Mint, 4 oz Tube (3 Tubes)

Strengthens and remineralizes enamel.
Reduces plaque and freshens breath.
Fluoride-free and family safe.

Main Highlights

ENAMEL-STRENGTHENING HYDROXYAPATITE TOOTHPASTE - Strengthen and remineralize enamel with XyloBurst’s fluoride-free hydroxyapatite formula - designed to protect teeth, smooth surfaces, and naturally brighten your smile.
THE POWER OF XYLITOL - Made with xylitol, this hydroxyapatite toothpaste helps reduce plaque buildup, balance oral pH, and naturally freshen breath - without causing sensitivity.
TRIPLE-ACTION FORMULA - Powered by CoQ10, green tea extract, and tea tree oil, this advanced formula delivers comprehensive care by supporting clean, healthy teeth and gums. The cool mint leaves your breath fresh and revitalized.
FLUORIDE-FREE & SAFE FOR THE WHOLE FAMILY - Made with premium natural ingredients and completely free from fluoride, SLS, parabens, preservatives, and artificial colors or sweeteners. Non-GMO, vegan, gluten-free, and cruelty-free.
TRUSTED BY DENTAL PROFESSIONALS - Recommended by healthcare experts and made in the USA, this daily-use xylitol toothpaste is your go-to solution for lasting oral health and confident smiles.

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured

19% OffFree Shipping

Promotes gum health effectively.
Whitens teeth while cleaning.
Safe for the whole family.

Main Highlights

APPROPRIATE FOR GUM HEALTH & ENAMEL REPAIR: A powerhouse next generation formula for gum health by harnessing the strength of Nano Hydroxyapatite (NHA)!
REMINERALIZES & WHITENS TEETH: Thanks to its innovative formula with Nano Hydroxyapatite (NHA), our toothpaste not only effectively cleans your teeth but also aids in the remineralization process. As a result, it improves your overall tooth enamel health and helps to brighten those pearly whites
BIOCOMPATIBLE: Free from Fluoride, Sulfates, Parabens & Artificial Flavors & Colors - we meticulously crafted our product to be 100% biocompatible, ensuring it’s safe for daily use and non-toxic when used as directed. A perfect way to take your oral hygiene routine to the next level!
APPROPRIATE FOR SENSITIVE TEETH: Gentle yet effective, it provides a soothing and refreshing experience for the whole family. Embrace an oral care routine designed for a luxurious experience
TASTE THE ELA MINT FUSION: A delightful fusion of refreshing mint, antioxidant-rich green tea, with a hint of cardamom. The invigorating mint leaves your breath feeling fresh & revitalized, with just a touch of cardamom adding a unique, yet welcome twist to your brushing experience. Say goodbye to the bland & mundane - say hello to a toothpaste flavor that excites your taste buds every time you brush

Davids Hydroxi Fluoride Free Nano Hydroxyapatite Toothpaste for Remineralizing Enamel & Sensitive Relief, Whitening, Antiplaque, SLS Free, Natural Peppermint, 5.25oz, Made in USA

Davids Hydroxi Fluoride Free Nano Hydroxyapatite Toothpaste for Remineralizing Enamel & Sensitive Relief, Whitening, Antiplaque, SLS Free, Natural Peppermint, 5.25oz, Made in USA

Natural ingredients for safe whitening.
Hydroxyapatite remineralizes enamel effectively.
Gentle on sensitive teeth relief.

Main Highlights

Features Hydroxi, our proprietary formulation of Nano Hydroxyapatite (n-HA) - the same ingredient that naturally makes up 97% of your teeth material, and carefully selected naturally sourced and naturally derived ingredients. We eliminated the fluoride and replaced it with this biocompatible ingredient to remineralize your enamel, reduce teeth sensitivity and naturally whiten.
Safe & Gentle Whitening – micro polishing agents gently remove surface stains to safely whiten without causing the sensitivity normally found with peroxide or other bleaching agents. RDA (abrasive rating) of 101 to effectively remove plaque and surface stains while being enamel safe for daily brushing. Safe range per ADA (American Dental Association).
Bioactive Sensitive Relief - most sensitive toothpastes uses Potassium Nitrate (nerve numbing drug) to temporarily numb the tooth nerves. We use Hydroxyapatite (n-HA) to reduce sensitivity by remineralizing the enamel and passageways (tubules) to the nerves.
Clean & Safe Ingredients – we use only premium ingredients derived from plants and the earth, with no animal by-products (vegan). Fluoride Free, Sulfate Free (no SLS), EWG VERIFIED. No Artificial Flavors, Colors, or Preservatives. Birch xylitol used to improve oral health.
Healthy Mouth – formulated to restore a healthy PH balance and support your mouth’s natural oral microbiome. Plaque is the main enemy of teeth and Davids is designed to aggressively stop plaque from forming and reduce existing plaque buildup, while leaving your mouth feeling minty fresh and exceptionally clean. Healthy mouth for a healthy you.

Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Remineralizing, Natural, Sensitive Teeth, SLS Free, Xylitol Nano-Hydroxyapatite Toothpaste for Adults, Mint 4oz (USA Made)

Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Remineralizing, Natural, Sensitive Teeth, SLS Free, Xylitol Nano-Hydroxyapatite Toothpaste for Adults, Mint 4oz (USA Made)

NASA-inspired enamel repair technology.
Clinically proven 10% effectiveness.
Fluoride-free and safe for everyone.

Main Highlights

NASA-INSPIRED ENAMEL REPAIR: Developed from NASA's space research, our 10% Nano Hydroxyapatite toothpaste restores and strengthens enamel, better than fluoride, without the harmful side effects. Achieve next-level protection and care for your teeth with every brush.
CLINICALLY PROVEN 10% NANO HYDROXYAPATITE: Unlike other brands that hide their Nano-Hydroxyapatite percentages, our toothpaste contains the full 10% Nano Hydroxyapatite—the clinically proven amount required for effective enamel restoration. Our nano-sized particles are precisely engineered to fill the microscopic pores in your teeth, delivering superior remineralization and protection.
NATURAL WHITENING, NO SENSITIVITY: Say goodbye to harsh bleaching agents. Our nano hydroxyapatite toothpaste smooths and whitens teeth by filling micro-lesions in the enamel, leaving you with a glossier, brighter smile—without causing sensitivity.
FLUORIDE FREE & SAFE FOR ALL AGES: Our toothpaste is completely fluoride-free, offering a safe alternative for those looking to avoid the negative health impacts of fluoride. Our nHa toothpaste is made with biocompatible ingredients, safe if swallowed and recommended by dentists nation-wide.
MADE IN USA WITH CLEAN, NATURAL INGREDIENTS: Made in the USA with premium, natural ingredients. Our toothpaste is fluoride-free, SLS-free, with birch xylitol to promote oral health. No artificial colors or flavors—just clean, gentle care for your mouth.