10 Best Eye Gel Drops For Dry Eyes Preservative Free of 2025

Last updated on 07/18/2025
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Best Choice
1
9.8
Exceptional
TheraTears Liquid Gel Nighttime Eye Drops for Dry Eyes, 30 Vials, 30 Count (Pack of 2)
TheraTears
TheraTears Liquid Gel Nighttime Eye Drops for Dry Eyes, 30 Vials, 30 Count (Pack of 2)
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Why We Love It
  • Soothing overnight relief provided.
  • Natural electrolytes promote hydration.
  • Preservative-free for sensitive comfort.
Main Highlights
  • IMMEDIATE DRY EYE RELIEF: TheraTears Lubricating Liquid Gel Eye Drops provide immediate, long-lasting relief of dry eye symptoms
  • HYDRATING EYE DROPS: TheraTears Nighttime dry eye drops have 4X the lubrication* for a subtly thicker, extra hydrating experience for tired, dry eyes while you sleep; *vs. TheraTears Original
  • PRESERVATIVE FREE EYE DROPS: These eye drops for dry eyes are formulated with the 5 vital electrolytes found in natural tears and are individually sealed for preservative free eye drops in a single-use vial
  • CREATED BY AN OPHTHALMOLOGIST: TheraTears was created by an ophthalmologist after 18 years of research for a one-of-a-kind eye drop
  • DOCTOR RECOMMENDED: Doctor recommended and created to bring balance and hydration to dry eyes
9.8
Exceptional
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Best Value
2
9.6
Superb
Save 28%
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
Systane
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
28% OffFree Shipping
Why We Love It
  • Fast hydration for dry eyes.
  • Preservative free for sensitive users.
  • Compatible with all contact lenses.
Main Highlights
  • Hydrates fast and provides long-lasting relief for dry eyes
  • Preservative free eye drops
  • Contains hyaluronate for advanced hydration
  • Safe for use with all contact lenses
  • Extra moisturizing eye drops for sensitive eyes
9.6
Superb
Save 28%
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3
9.6
Superb
Save 30%
Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count
Systane
Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count
30% OffFree Shipping
Why We Love It
  • Triple-action relief for dry eyes.
  • Hydrating formula supports long-lasting moisture.
  • Gentle and preservative-free for sensitivity.
Main Highlights
  • Triple-Action Dry Eye Relief: Systane Pro Preservative Free Eye Drops hydrate, restore and protect dry eyes for long-lasting relief
  • Long-Lasting Hydration: Systane Pro Preservative Free lubricating eye drops are formulated with Hyaluronate, a moisturizer that occurs naturally in tears, to support extended hydrationfor all types of dry eye relief
  • Tear Evaporation Protection: This unique formula enhanced with lipid nanodroplets helps lock in moisture and reduce tear evaporation
  • Preservative-Free Formula: The gentle, preservative-free formula is ideal for sensitive eyes
  • Trusted Brand: Systane is a trusted name in eye care, recommended by eye care professionals for its effective and reliable relief from dry eyes
  • Convenient Size: The 10mL oz bottle is perfect for daily use, offering you triple action dry eye relief at your fingertips
  • Contact Lens Friendly^: safe for use with soft contact lenses
9.6
Superb
Save 30%
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4
9.6
Superb
Save 20%
iVIZIA Lubricant Eye Gel for Severe and Nighttime Dry Eye Relief, Preservative-Free, Moisturizing, 30 Sterile Single-Use Vials Packaging May Vary
iVIZIA
iVIZIA Lubricant Eye Gel for Severe and Nighttime Dry Eye Relief, Preservative-Free, Moisturizing, 30 Sterile Single-Use Vials Packaging May Vary
20% OffFree Shipping
Why We Love It
  • Thicker formula for overnight relief.
  • Hydrating polymers protect and moisturize.
  • Preservative-free for sensitive eyes.
Main Highlights
  • Your Dry Eyes Deserve Better: Thicker formula for overnight use, our gel provides more lubrication and moisture than our daytime formula and is ideal to relieve severe dry eye symptoms.
  • Free of Irritating Preservatives: Sterile, preservative-free, and can be used before or after eye surgery.
  • Sterile Single-Use Vials: iVIZIA Lubricant Eye Gel is offered in preservative-free sterile, single-use vials that are convenient and easy to use for severe dry eye or nighttime use.
  • iVIZIA – We See a Better Way: for healthy, comfortable eyelids
9.6
Superb
Save 20%
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5
9.5
Superb
Save 10%
Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)
Systane
Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)
10% OffFree Shipping
Why We Love It
  • Dr Recommended for eye care.
  • Thick protection for dry eyes.
  • Convenient drop, gel-like relief.
Main Highlights
  • #1 Dr Recommended Brand of Artificial Tears*
  • Thicker eye drop formulation that creates a protective shield over your eyes.
  • Convenience of a drop with a protection of a gel.
  • For the temporary relief of burning and irritation due to dryness of the eye
  • NOTE: PRODUCT PACKAGING MAY VARY
9.5
Superb
Save 10%
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6
9.3
Superb
Save 31%
Refresh Celluvisc Lubricant Eye Gel Preservative-Free Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
Refresh
Refresh Celluvisc Lubricant Eye Gel Preservative-Free Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
31% OffFree Shipping
Why We Love It
  • Original strength formula works wonders.
  • Relieves dry eye discomfort quickly.
  • Trusted by doctors for decades.
Main Highlights
  • Original strength gel formula
  • Relieves dry, burning, irritated eyes
  • Alleviates discomfort
  • Keeps eyes feeling better longer
  • doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey
9.3
Superb
Save 31%
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7
9.2
Superb
Save 20%
Refresh Optive Gel Drops Lubricant Eye Gel For Dry Eyes, 0.33 Oz Sterile
Refresh
Refresh Optive Gel Drops Lubricant Eye Gel For Dry Eyes, 0.33 Oz Sterile
20% OffFree Shipping
Why We Love It
  • Extended relief for eye dryness.
  • Comprehensive gel formula for comfort.
  • Hydrocell technology ensures lasting hydration.
Main Highlights
  • Extended relief plus protection for dry, irritated eyes
  • Our most comprehensive gel formula
  • Anytime relief, day or night
  • Feels like a drop but works like a gel for lasting comfort
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • #1 doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
9.2
Superb
Save 20%
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8
9.1
Superb
Save 11%
Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile
Refresh
Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile
11% OffFree Shipping
Why We Love It
  • Original strength gel formula.
  • Doctor recommended and trusted.
  • Long-lasting eye comfort relief.
Main Highlights
  • Original strength gel formula
  • Relieves dry, burning, irritated eyes
  • Alleviates discomfort
  • Keeps eyes feeling better longer
  • Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey
  • For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun
9.1
Superb
Save 11%
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9
9.0
Superb
Save 18%
Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
Refresh
Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
18% OffFree Shipping
Why We Love It
  • Rapid relief for dry eyes.
  • Soothes and prevents irritation.
  • Convenient single-use on-the-go vials.
Main Highlights
  • FAST-ACTING: Rapid relief to comfort dry, irritated eyes
  • LASTING RELIEF: Soothes and prevents further irritation
  • TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
  • PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based Flaxseed Oil (inactive ingredients) which contains omega-3s
  • ADVANCED HYDRATION: Innovated with patented HydroCell technology that enables rehydration
  • ON-THE-GO VIALS: 30 sterile single-use vials per carton that are easy and safe to use as often as needed
  • TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
  • FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
9.0
Superb
Save 18%
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10
8.9
Excellent
Save 48%
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)
Systane
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)
48% Off
Why We Love It
  • Rapid relief for sensitive eyes.
  • Safe and preservative-free formula.
  • Advanced nano droplets enhance coverage.
Main Highlights
  • Fast acting hydration for sensitive eyes
  • Preservative free tear evaporation protection
  • Nano droplets for better coverage
8.9
Excellent
Save 48%
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