10 Best Eye Drops For Contacts Preservative Free of 2025
Last updated on 09/26/2025
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1
Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 60 Single-Use Containers
Refresh
29% OffFree Shipping
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Refresh
Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 60 Single-Use Containers
29% OffFree Shipping
Why we love it
- Fast relief for dry eyes.
- Lasting comfort and protection.
- Convenient single-use vials available.
Main Highlights
- FAST-ACTING: Rapid relief to comfort dry, irritated eyes
- LASTING RELIEF: Soothes and prevents further irritation
- TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
- PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based Flaxseed Oil (inactive ingredients) which contains omega-3s
- ADVANCED HYDRATION: Innovated with patented HydroCell technology that enables rehydration
- ON-THE-GO VIALS: 60 sterile single-use vials per carton that are easy and safe to use as often as needed
- TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
- FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
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Value for Money
2
Refresh Optive Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count
Refresh
28% OffFree Shipping
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Refresh
Refresh Optive Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count
28% OffFree Shipping
Why we love it
- Lubricates and hydrates effectively.
- Relieves dryness quickly and efficiently.
- Perfect for sensitive eyes.
Main Highlights
- Dual-action formula lubricates and hydrates
- Relieves mild symptoms of eye dryness
- Works fast by delivering soothing moisture
- Preservative-free for sensitive eyes
- Value size: 60 on-the go, single-use vials
- Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
- The selling brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
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3
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
Systane
31% Off
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Systane
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
31% Off
Why we love it
- Fast hydration for dry eyes.
- Preservative free for sensitive users.
- Compatible with all contact lenses.
Main Highlights
- Hydrates fast and provides long-lasting relief for dry eyes
- Preservative free eye drops
- Contains hyaluronate for advanced hydration
- Safe for use with all contact lenses
- Extra moisturizing eye drops for sensitive eyes
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4
Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count
Systane
27% OffFree Shipping
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Systane
Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count
27% OffFree Shipping
Why we love it
- Triple-action relief for dry eyes.
- Hydrating formula supports long-lasting moisture.
- Gentle and preservative-free for sensitivity.
Main Highlights
- Triple-Action Dry Eye Relief: Systane Pro Preservative Free Eye Drops hydrate, restore and protect dry eyes for up to 12 hours of relief
- Long-Lasting Hydration: Systane Pro Preservative Free lubricating eye drops are formulated to support extended hydration for all types of dry eye relief
- Tear Evaporation Protection: This unique formula helps lock in moisture and reduce tear evaporation
- Preservative-Free Formula: The gentle, preservative-free formula is ideal for sensitive eyes
- Trusted Brand: Systane is a trusted name in eye care, recommended by eye care professionals for its effective and reliable relief
- Convenient Size: The 10mL bottle is perfect for daily use, offering you triple action dry eye relief at your fingertips
- Contact Lens Friendly*: safe for use with soft contact lenses
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5
LUMIFY Redness Reliever Preservative Free Eye Drops, 20 Single Use Vials, Fast Acting, Only PF Drop for Whiter & Brighter Looking Eyes, Relieves Red Eyes, Works in 1 Min, Lasts Up to 8 Hours
LUMIFY
24% OffFree Shipping
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LUMIFY
LUMIFY Redness Reliever Preservative Free Eye Drops, 20 Single Use Vials, Fast Acting, Only PF Drop for Whiter & Brighter Looking Eyes, Relieves Red Eyes, Works in 1 Min, Lasts Up to 8 Hours
24% OffFree Shipping
Why we love it
- Restores natural eye whiteness.
- Works quickly and lasts long.
- Gentle on sensitive eyes.
Main Highlights
- EYE DROPS FOR RED EYES: From the eye care experts at Bausch & Lomb, LUMIFY Preservative Free Eye Drops help restore your eyes natural whiteness & reveal your eyes' natural radiance. These red eye drops work within 1 minute & last up to 8 hours
- PRESERVATIVE FREE EYE DROPS: Compared to other redness relief eye drops, LUMIFY is the only OTC eye drop to contain low-dose brimonidine that selectively targets redness & helps lower risk of certain side effects seen with other OTC redness relievers when used as directed
- PRESERVATIVE FREE REDNESS RELIEVER: The LUMIFY eye drops do not contain bleach or dyes. 95% showed significant redness reduction in 1 minute. They are the first and only preservative free redness reliever eye drops and are formulated to be gentle on sensitive eyes
- AMAZING LOOKING EYES: We understand how important eyes are and despite all eye creams, mascara, eyeliners, and eyeshadows, you won't look your best with red eyes. Our redness relief eye drops help eyes look brighter and whiter to help restore their natural glow
- DEVELOPED BY EYE CARE EXPERTS: For over 150 years, the experts at Bausch + Lomb have focused on innovation & quality in eye care products, from contact lenses and solutions to eye drops for allergies and eye itching, ointments, eye vitamins, and more
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6
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
Refresh
27% OffFree Shipping
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Refresh
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
27% OffFree Shipping
Why we love it
- Preservative-free for sensitive eyes.
- Instant moisture for dry eyes.
- Convenient single-use vials.
Main Highlights
- Original strength, preservative-free formula
- Relieves mild symptoms of eye dryness
- Instantly moisturizes and lubricates
- Designed to act like your own natural tears
- Great for sensitive eyes
- Value size. 50 on-the go, single-use vials
- Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
- The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
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7
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)
Systane
Free Shipping
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Systane
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)
Free Shipping
Why we love it
- Rapid relief for sensitive eyes.
- Safe and preservative-free formula.
- Advanced nano droplets enhance coverage.
Main Highlights
- Fast acting hydration for sensitive eyes
- Preservative free tear evaporation protection
- Nano droplets for better coverage
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8
Refresh Digital PF Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count (Pack of 1)
Refresh
7% OffFree Shipping
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Refresh
Refresh Digital PF Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count (Pack of 1)
7% OffFree Shipping
Why we love it
- Fast relief from eye discomfort.
- Soothes all three tear layers.
- Prevents tear evaporation effectively.
Main Highlights
- Preservative-free formula acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use
- Delivers soothing hydration by supporting all three tear film layers
- Helps prevent tears from evaporating due to lipid layer deficiencies
- Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
- 30 single-use vials
- The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
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9
Refresh Relieva PF Lubricant Eye Drops for Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count
Refresh
19% OffFree Shipping
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Refresh
Refresh Relieva PF Lubricant Eye Drops for Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count
19% OffFree Shipping
Why we love it
- Preservative free for sensitive eyes.
- Hydrocell technology ensures lasting hydration.
- Relief after LASIK and surgeries.
Main Highlights
- Preservative free formula relieves discomfort due to dry, irritated eyes
- Prevents further irritation
- Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
- Recommended for sensitive eyes
- Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
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10
Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)
Systane
31% Off
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Systane
Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)
31% Off
Why we love it
- Fast-Acting Hydration for Relief.
- Sensitive Eyes Receive Gentle Care.
- Protection Against Tear Evaporation.
Main Highlights
- Preservative-Free Lubricant Eye Drops
- Fast-Acting Hydration and lasting dry eye relief
- Moisture rich formula eye drops for sensitive eyes
- Tear evaporation protection for high-performance dry eye symptom relief that lasts
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