10 Best Digestive Enzymes For Weight Loss of 2025

Last updated on 07/16/2025
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1
9.9
Exceptional
Wholesome Wellness Digestive Enzymes 1000MG Plus Prebiotics & Probiotics Supplement, 180 Capsules, Organic Plant-Based Vegan Formula for Digestion & Lactose with Amylase & Bromelain,3-6 Months Supply
Wholesome Wellness
Wholesome Wellness Digestive Enzymes 1000MG Plus Prebiotics & Probiotics Supplement, 180 Capsules, Organic Plant-Based Vegan Formula for Digestion & Lactose with Amylase & Bromelain,3-6 Months Supply
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Why We Love It
  • Powerful digestive enzyme blend.
  • Supports gut health effectively.
  • Made with organic ingredients.
Main Highlights
  • Get Digestive Comfort Now – Ultra Strength 1000 MG Dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics. Get results & relief fast with more than double the dose of other digestive enzyme supplements. Using organic, systemic, Dr. formulated, & plant based ingredients to ensure the best healthy digestion for adult men & women. Anti bloating, flatulence, fat, pancreatic, & bowel cleansing with Turmeric, Ginger, Papaya, Pectin, Bladderwrack & more.
  • Goodbye Hard-to-Digest Foods – This formula features our Advanced Multi Enzyme System to help you digest fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. Immune-Boosting Probiotic – The gut, biofilm & gallbladder is home to 50% of the body’s immune repair response and this supplement contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.
  • Relieve Gas, Belly Bloating / Bloat, Constipation, Leaky, Indigestion, Reflux, Belching & Acid Discomfort! Aid gut health, beauty & bloated stomach comfort. Prebiotic fiber, probiotic encapsulation(Lactobacillus acidophilus, plantarum, casei, salivarius, bulgaricus and Bifidobacterium lactis, bifidum, breve, longum), & enzymes support gut flora bacteria, bile, nutrient absorption, motility, & enzyme levels your body isn't producing as you age.
  • Complete digestive enzyme pills complex blend with essential organic blue agave heart, inulin, amylase / amilasa, papain, protease A, invertase, cellulase, hemicellulase, lactase, lipase / lipasa, alpha-galactosidase, fungal pepsin, glucomylase, & bromelina & bromelain supplement. Plus your probiotic supplement and prebiotic supplement (pre & pro) at the same time. All in a convenient purified cap / capsule form which you can open and take as a chewable with dietary nutrients, super food or meal
  • Proudly made in the USA in a GMP certified manufacturing facility, 3rd Party Tested, and a 100% satisfaction money back guarantee. If you are not satisfied with our products for any reason, let us know and we’ll make it right. This product is vegan, non-GMO, pure, natural, gluten free, cGMP, wise, dairy free, zen, organic ingredients and is free of soy, peanuts, eggs, gelatin, ox, shellfish, artificial sweeteners, colors, & flavors.
9.9
Exceptional
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2
9.7
Exceptional
Physician's CHOICE Advanced Gut Health Bundle: 60 Billion Probiotics 30ct + Digestive Enzymes 60ct for Digestive, Gut, and Immune Health Supports Occasional Constipation, Diarrhea, Gas, and Bloating
Physician's CHOICE
Physician's CHOICE Advanced Gut Health Bundle: 60 Billion Probiotics 30ct + Digestive Enzymes 60ct for Digestive, Gut, and Immune Health Supports Occasional Constipation, Diarrhea, Gas, and Bloating
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Why We Love It
  • Optimal gut health support.
  • Enhanced nutrient absorption benefits.
  • Convenient bundle for savings.
Main Highlights
  • Optimal Gut Health: Our bundle combines the power of our 60 billion CFU probiotic with Digestive Enzymes to promote a balanced and healthy gut environment. Say goodbye to digestive discomfort.
  • Enhanced Nutrient Absorption: Our digestive enzymes assist in breaking down food more effectively, helping your body absorb essential nutrients from your diet.
  • Survives the Gut: From start to finish - this probiotic is designed to survive the gut & maximize the colonization of our strains.
  • Digestive Comfort: Bid farewell to bloating, gas, and indigestion. The combination of probiotics and digestive enzymes in this bundle supports smoother digestion, reducing discomfort after meals and supporting a flatter stomach.
  • Convenience and Savings: By bundling our best-selling probiotics and digestive enzymes together, we offer you the convenience of a comprehensive gut health solution in one package. Plus, you’ll save money compared to purchasing these products separately, making it a cost-effective choice for your health and wellness regimen.
9.7
Exceptional
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9.6
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Physician's CHOICE Probiotics for Weight Management & Bloating - 6 Probiotic Strains - Prebiotics - Key ingredient Cayenne - Supports Gut Health - Weight Management for Women & Men - Green Tea - 30 CT
Physician's CHOICE
Physician's CHOICE Probiotics for Weight Management & Bloating - 6 Probiotic Strains - Prebiotics - Key ingredient Cayenne - Supports Gut Health - Weight Management for Women & Men - Green Tea - 30 CT
10% OffFree Shipping
Why We Love It
  • Supports effective weight management.
  • Promotes gut health and balance.
  • Quality ingredients, safely tested.
Main Highlights
  • Supports Weight Management: In a Clinical study, 100 patients lost an average of 30 lbs in 90 days taking 300 mg of Greenselect Phytosome daily with a reduced-calorie diet & exercise. Same great product you love, with a new look. Packaging May Vary!
  • Supports Gut & Bloating: Contains Probiotics & organic prebiotics with natural green tea extract. With our weight management probiotics you can be assured that our formula has been formulated to you on your weight management journey
  • Supports Digestive Health & Balance: A daily probiotic and organic prebiotic with digestive enzymes to promote gut health and balance. These strains act together in supporting gut health. Our formula contains Capsimax to help promote weight management
  • Probiotics to Support Weight Management for Women & Men: Our probiotic for women & men is designed to support weight loss management & digestive health. Thin30 is a useful diet aid that is a great addition to your diet & exercise regimen.
  • Safety Assured Standard of Quality: Our Probiotic is 3rd-party tested for purity, manufactured in the USA using imported and domestic ingredients in a cGMP compliant facility. Our probiotics for women & men for weight management are non-GMO
9.6
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4
9.5
Superb
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules
Pure Encapsulations
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules
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Why We Love It
  • Supports nutrient absorption effectively.
  • Aids digestion of complex foods.
  • Free from allergens and GMOs.
Main Highlights
  • Nutrient Absorption: Contains a mixture of vegetarian enzymes developed to support nutrient bioavailability and absorption; supports digestion*
  • Supports Digestion: Facilitates the normal breakdown of proteins, peptides, polysaccharides and disaccharides; assists with dairy, fiber, and protein digestion*
  • Digestive Enzymes: Offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range
  • Dairy Enzyme Blend: This vegetarian enzyme blend supports digestion of dairy, sugar, lactose, and certain complex carbs; supports relief from occasional gas or bloating
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
9.5
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5
9.3
Superb
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NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules
NOW Foods
NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules
49% OffFree Shipping
Why We Love It
  • Supports healthy digestion efficiently.
  • Breaks down nutrients effectively.
  • GMP quality assures potency.
Main Highlights
  • SUPPORTS HEALTHY DIGESTION*: NOW Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion.* Take one capsule with a meal
  • BREAKS DOWN FATS, CARBS, AND PROTEINS*/OPTIMIZES NUTRIENT AVAILABILITY*: Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein*
  • CERTIFICATIONS/CLASSIFICATIONS: Soy Free, Made without Gluten, Keto Friendly
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
  • Packaged in the USA by a family owned and operated company since 1968
9.3
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9.2
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Enzymedica Lypo Gold, Digestive Enzymes for Fat Digestion, Offers Fast Acting Gas & Bloating Relief, 60 Count
Enzymedica
Enzymedica Lypo Gold, Digestive Enzymes for Fat Digestion, Offers Fast Acting Gas & Bloating Relief, 60 Count
33% OffFree Shipping
Why We Love It
  • Efficiently breaks down fatty foods.
  • Supports keto diets effectively.
  • Vegan and clean label certified.
Main Highlights
  • Fat Digestion Expert: Packed with the fat-digesting Lipase enzyme, Lypo Gold efficiently breaks down a wide range of fatty foods, whether they're the healthy fats in avocado and salmon or the greasy indulgences in fried treats, burgers and more
  • Keto-Friendly Companion: Helpful for keto dieters and those without gallbladders, this supplement breaks down fatty foods, carbs and proteins, relieving gas and bloating*
  • Effective All the Way Through: Our proprietary Thera-blend enzymes are formulated for optimal activity throughout the digestive system's varying pH levels, providing faster relief and maximum digestive support*
  • Dosage: Just 1 capsule daily breaks down up to 22g fat, 4g protein and 32g carbs; Take more than 1 capsule as needed; Contains no gluten, milk, casein, soy, egg, artificial colors, flavors, or GMOs; Vegan, Kosher and Clean Label Project Certified
  • Making a Difference: Enzymedica products harness the power of the finest natural ingredients for maximum effectiveness; We create quality products without compromise while championing initiatives that support the well-being of people and our planet
9.2
Superb
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7
9.2
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HUM Flatter Me Digestive Enzymes Bloating Supplement - Fast-Acting Bloat Relief for Digestive Health & Debloating Multi Enzyme | Bloat Pills, Anti Bloat Pills, Vegan 60 Servings
HUM
HUM Flatter Me Digestive Enzymes Bloating Supplement - Fast-Acting Bloat Relief for Digestive Health & Debloating Multi Enzyme | Bloat Pills, Anti Bloat Pills, Vegan 60 Servings
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Why We Love It
  • Fast relief from bloating.
  • Supports healthy digestion naturally.
  • Clinically tested for effective results.
Main Highlights
  • Fast-acting, 30 Minute Debloat Formula– Combat bloating in just 30 minutes with our blend of 18 full-spectrum digestive enzymes like lipase, amylase, and bromelain, designed to break down proteins, carbs, fats, and fiber, promoting digestive health and bloating relief for women.
  • Natural Triple Herb Blend For Digestion Support – Our fast-acting formula is enhanced with a natural triple herb blend of ginger, peppermint, and fennel to support healthy digestion and nutrient absorption.
  • Clinically Tested Results You Can Feel – Flatter Me’s advanced digestive enzyme blend is clinically shown to reduce bloating in 30 minutes and by up to 2 inches after just one use.*
  • Clean and Clinically Studied. HUM products are Clean Label Project Certified, non-GMO, and rigorously tested to meet the highest standards of safety and quality, free from artificial flavors, sweeteners and colors.
  • How To Take – Take one capsule with a meal.
9.2
Superb
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8
9.1
Superb
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Enzymedica Digest Gold + ATPro, Maximum Strength Digestive Enzymes, Helps Digest Large Meals for Instant Bloating Relief, 45 Count
Enzymedica
Enzymedica Digest Gold + ATPro, Maximum Strength Digestive Enzymes, Helps Digest Large Meals for Instant Bloating Relief, 45 Count
25% OffFree Shipping
Why We Love It
  • Bloat relief for food lovers.
  • Boosts energy after meals.
  • Effective throughout the digestive system.
Main Highlights
  • For Food Lovers: Savor your favorite dishes worry-free; Our full-strength, bloat-busting digestive enzyme blend helps break down large meals faster, easing bloating and occasional indigestion for care-free indulgence*
  • ATPro Blend: Beat the post-meal blues and feel fueled with energy to power through your day; This unique formula features ATPro, a proprietary blend of ATP, Magnesium Citrate, Phytase and CoQ10 that helps fuel your body's cells*
  • Effective All the Way Through: Our proprietary Thera-blend enzymes are formulated for optimal activity throughout the digestive system's varying pH levels, providing faster relief and maximum digestive support*
  • Dosage: Just 1 capsule daily breaks down up to 34g fat, 16g protein and 86g carbs; Contains no gluten, milk, casein, soy, egg, artificial colors, flavors, or GMOs; Vegan, Kosher and Clean Label Project Certified
  • Making a Difference: Enzymedica products harness the power of the finest natural ingredients for maximum effectiveness; We create quality products without compromise while championing initiatives that support the well-being of people and our planet
9.1
Superb
Save 25%
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9
9.0
Superb
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Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables
Garden of Life
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables
24% OffFree Shipping
Why We Love It
  • Organic goodness in every tablet.
  • Supports healthy digestion naturally.
  • Convenient and tasty on-the-go.
Main Highlights
  • BREAK IT DOWN: Organic Digest+ offers 29 Certified Organic fruits and vegetables plus a select blend of 13 powerful digestive enzymes including bromelain and lactase to help with digestion after meals
  • MADE FROM WHOLE FOODS: Dr. Perlmutter formulated Digest+ to be a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs; We’ve also included prebiotic fiber from Organic Acacia to support the good bacteria in your gut
  • BACKED BY SCIENCE: Our Dr. Formulated Organic Digest+ is the first-ever Certified Organic and Non-GMO digestive enzyme formula that is made from real food and is delivered using Clean Tablet Technology to ensure optimal nutrient absorption
  • CONVENIENCE IN MIND: Transport to the tropics after every last bite; Enjoy the benefits of Organic Digest+ in a tropical flavored, shelf stable tablet thats size makes it easy to take on the go; Adults chew 1 tablet after each meal or snack
  • EXPERTLY FORMULATED: Our digestive supplement is proudly Dr. Formulated by David Perlmutter, MD and Third-Party Certified Non-GMO, Gluten-Free and Vegan; Made in the USA with no dairy, soy, gluten, peanuts or tree nuts
9.0
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10
8.8
Excellent
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Sports Research Digestive Enzymes with Probiotics & Ginger - Plant Based for Dairy, Protein, Sugar & Carbs - Non-GMO Verified & Vegan Friendly (90 Veggie Capsules)
Sports Research
Sports Research Digestive Enzymes with Probiotics & Ginger - Plant Based for Dairy, Protein, Sugar & Carbs - Non-GMO Verified & Vegan Friendly (90 Veggie Capsules)
12% OffFree Shipping
Why We Love It
  • Complete gut wellness support.
  • Eases stomach digestion effectively.
  • Quality assured and tested.
Main Highlights
  • COMPLETE GUT WELLNESS: With 15 enzymes plus probiotics and ginger— these veggie capsules are here to promote better nutrient absorption, encourage proper digestion, and help promote stomach regularity*
  • HELP EASE STOMACH DIGESTION: Digestive Enzymes from Sports Research is specially formulated to help you digest proteins, fats, fruits, vegetable fiber, dairy products, and carbohydrates, resulting in better nutrient absorption and less digestive discomfort*
  • BEAT THE BLOAT: Replenishes enzymes that may decline with age. Our plant-based digestive enzymes with probiotics and ginger work synergistically to help tackle hard-to-digest foods and stomach bloating*
  • QUALITY ASSURED: We hold all of our supplements to a higher standard. Rest assured that your digestive enzymes capsules are manufactured in a cGMP-compliant USA facility and third-party tested for quality. Our digestive enzymes capsules are Non-GMO Project Verified, Vegan Friendly, and free of gluten, soy, and unwanted fillers
  • THE SPORTS RESEARCH DIFFERENCE: Founded in Southern California in 1980, Sports Research is a family-owned business born from a passion for fitness and wellness. Our goal is to embrace the sport of life through research-backed products created for every body—inside and out (Please remove product label before recycling bottle)
8.8
Excellent
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