10 Best Contact Lens Eye Drops Preservative Free of 2025

Last updated on 07/16/2025
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Best Choice
1
9.7
Exceptional
Save 30%
Refresh Optive Lubricant Eye Drops Preservative-Free Tears, 0.01 fl oz (0.4 mL), 60 Single-Use Containers
Refresh
Refresh Optive Lubricant Eye Drops Preservative-Free Tears, 0.01 fl oz (0.4 mL), 60 Single-Use Containers
30% OffFree Shipping
Why We Love It
  • Lubricates and hydrates effectively.
  • Relieves dryness quickly and efficiently.
  • Perfect for sensitive eyes.
Main Highlights
  • Dual-action formula lubricates and hydrates
  • Relieves mild symptoms of eye dryness
  • Works fast by delivering soothing moisture
  • Preservative-free for sensitive eyes
  • Value size: 60 on-the go, single-use vials
  • Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
  • The selling brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
9.7
Exceptional
Save 30%
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Best Value
2
9.5
Superb
Purilens Plus Preservative-Free Contact Lens Saline 120ml (4 fl. oz.) 3 Pack
Purilens
Purilens Plus Preservative-Free Contact Lens Saline 120ml (4 fl. oz.) 3 Pack
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Why We Love It
  • Exceptional comfort for sensitive eyes.
  • Ideal for scleral lens users.
  • Preservative-free for ultimate safety.
Main Highlights
  • Includes: 3 4-fl. oz. bottles of Purilens Plus Preservative-Free Saline Solution
  • pH-balanced to eye’s natural tears for superior comfort
  • Maximizes contact lens comfort and clarity
  • Indicated for use as an insertion solution for scleral lenses
  • For dry and sensitive eyes
9.5
Superb
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3
9.5
Superb
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
Refresh
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
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Why We Love It
  • Preservative-free for sensitive eyes.
  • Instant moisture for dry eyes.
  • Convenient single-use vials.
Main Highlights
  • Original strength, preservative-free formula
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
  • Great for sensitive eyes
  • Value size. 50 on-the go, single-use vials
  • Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
  • The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
9.5
Superb
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4
9.4
Superb
Save 39%
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
Systane
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
39% OffFree Shipping
Why We Love It
  • Fast hydration for dry eyes.
  • Preservative free for sensitive users.
  • Compatible with all contact lenses.
Main Highlights
  • Hydrates fast and provides long-lasting relief for dry eyes
  • Preservative free eye drops
  • Contains hyaluronate for advanced hydration
  • Safe for use with all contact lenses
  • Extra moisturizing eye drops for sensitive eyes
9.4
Superb
Save 39%
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5
9.2
Superb
Save 19%
Refresh RELIEVA PF Preservative-Free Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
Refresh
Refresh RELIEVA PF Preservative-Free Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
19% OffFree Shipping
Why We Love It
  • Preservative free for sensitive eyes.
  • Hydrocell technology ensures lasting hydration.
  • Relief after LASIK and surgeries.
Main Highlights
  • Preservative free formula relieves discomfort due to dry, irritated eyes
  • Prevents further irritation
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • Recommended for sensitive eyes
  • Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
9.2
Superb
Save 19%
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6
9.1
Superb
Bausch + Lomb ScleralFil Preservative Free Saline Solution for Scleral Lenses, Buffered Isotonic Rinsing & Insertion Solution for Soft and Rigid Gas Permeable Contacts, Single-Use Vials, 30 Count
Bausch + Lomb
Bausch + Lomb ScleralFil Preservative Free Saline Solution for Scleral Lenses, Buffered Isotonic Rinsing & Insertion Solution for Soft and Rigid Gas Permeable Contacts, Single-Use Vials, 30 Count
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Why We Love It
  • Sterile solution ensures safety.
  • Buffered for optimal comfort.
  • Travel-friendly packaging convenience.
Main Highlights
  • SALINE SOLUTION FOR CONTACT LENSES: ScleralFil is a sterile, buffered isotonic saline solution for scleral, soft and rigid gas permeable contact lenses
  • BUFFERED CONTACT LENS SOLUTION: The sterile saline solution is buffered to maintain pH, and is suitable for use with scleral lenses
  • TRAVEL SIZE CONTACT SOLUTION: ScleralFil is packaged in travel-friendly, single-use 10ml vials that stand upright. Simply twist-off the plastic cap to open the vial
  • EYE CARE EXPERTS: For over 150 years, Bausch + Lomb has focused on innovation and quality in our eye care products, from contact lenses and solutions to eye drops, ointments, eye vitamins and more
  • EYE DROPS and MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, and ointments to make sure your eyes feel comfortable, moisturized, and protected
9.1
Superb
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7
9.0
Superb
Biotrue Hydration Boost for Contacts, Rehydrating Eye Drops for Dry Eyes, Preservative Free, Refreshes, Lubricates & Moisturizes Lenses, Rewetting Eye Drops, 0.33 FL Oz (Pack of 1)
Biotrue
Biotrue Hydration Boost for Contacts, Rehydrating Eye Drops for Dry Eyes, Preservative Free, Refreshes, Lubricates & Moisturizes Lenses, Rewetting Eye Drops, 0.33 FL Oz (Pack of 1)
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Why We Love It
  • Naturally inspired ingredients enhance comfort.
  • Lasting moisture keeps eyes hydrated.
  • Preservative-free for optimal safety.
Main Highlights
  • NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost for Contacts are enhanced with HA (Hyaluronan), Antioxidant (Protects HA from free radicals), and Electrolyte.
  • LASTING MOISTURE: For up to 8 hours of moisture (based on a laboratory study) and to help prevent deposit buildup.
  • REWETTING DROPS FOR CONTACT LENSES: Biotrue Hydration Boost for Contacts are the first preservative free multi-dose contact lens drops.
  • BIOTRUE CONTACT LENS DROPS: Not only are Biotrue Hydration Boost for Contacts free of preservatives but they are also pH balanced for comfort.
  • EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solutions to eye drops, vitamins, & ointments to help your contacts and eyes feel moisturized and protected.
9.0
Superb
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8
8.8
Excellent
Save 22%
Refresh RELIEVA FOR CONTACTS Lubricant Eye Drops For Use with Contact Lenses, 0.27 fl oz (8 mL)
Refresh
Refresh RELIEVA FOR CONTACTS Lubricant Eye Drops For Use with Contact Lenses, 0.27 fl oz (8 mL)
22% OffFree Shipping
Why We Love It
  • Innovative formula for contact lens.
  • Relieves discomfort and dryness effectively.
  • Compatible with all contact lenses.
Main Highlights
  • Innovative formula specially designed for contact lens wearers
  • Relieves mild to moderate symptoms of eye dryness, irritation, and discomfort associated with contact lens wear
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • You may keep your contacts in upon application
  • May also be used to lubricate and rewet soft and rigid gas permeable (RGP) contact lenses and to cushion lenses prior to application
8.8
Excellent
Save 22%
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9
8.7
Excellent
Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Clears and Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 1)
Biotrue
Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Clears and Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 1)
Free Shipping
Why We Love It
  • Naturally inspired hydrating ingredients.
  • Instant relief for dry eyes.
  • Preservative-free for enhanced comfort.
Main Highlights
  • NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
  • INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
  • Special preservative free, multi-dose bottle.
  • BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced for comfort.
  • EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solutions to eye drops, vitamins, & ointments to help your eyes feel moisturized and protected.
8.7
Excellent
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10
8.7
Excellent
Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
Refresh
Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
Free Shipping
Why We Love It
  • Provides fast dry eye relief.
  • Preservative-free for sensitive eyes.
  • Trusted brand with proven experience.
Main Highlights
  • ORIGINAL STRENGTH: Provides temporary relief for mild, occasional dry eye symptoms
  • FAST-ACTING: Instantly lubricates and moisturizes
  • PRESERVATIVE-FREE: Great for sensitive eyes
  • SOFT SQUEEZE MULTIDOSE BOTTLE: Features a double lockout system that keeps drops sterile
  • TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
  • FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
8.7
Excellent
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