10 Best Arthritis Pain Relief Cream of 2025

Last updated on 07/19/2025

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Frankincense and Myrrh Arthritis Pain Reliever Therapy Lotion – Topical Arthritis Pain Relief Cream and Hydrating Skin Repair, Body Relief for Sciatica, Knee, Back, Joints, Neck, Hands, 3 Oz - 1 Pack

FRANKINCENSE & MYRRH

Frankincense and Myrrh Arthritis Pain Reliever Therapy Lotion – Topical Arthritis Pain Relief Cream and Hydrating Skin Repair, Body Relief for Sciatica, Knee, Back, Joints, Neck, Hands, 3 Oz - 1 Pack

Targets joint and muscle pain.
Fast acting relief guaranteed.
Easy to apply and use.

Main Highlights

TARGETS JOINT AND MUSCLE: Powerful relief for painful nerve, joint, and muscle pain in hands, wrists, elbows, knees, feet, ankles, neck, and back, including sciatica.
FAST ACTING RELIEF: Maximum strength cream penetrates skin quickly for fast, targeted relief with NO negative side effects. Satisfaction guaranteed -- see package for contact information.
EASY TO APPLY: The easy to apply arthritis relief lotion with easy to open flip top cap, temporarily relieves minor pain associated with inflammation, overuse, and stiff, sore muscles and joints.
PREMIUM INGREDIENTS. TRUSTED QUALITY: Blended with the highest quality ingredients including lanolin, shea & cocoa butter, menthol and 9 calming essential oils. Manufactured at an FDA registered facility in the U.S.
RECOMMENDED BY CLINICIANS TO RELIEVE PAIN: Over 3,000 U.S. physicians, nurse practitioners and clinicians actively recommend Frankincense & Myrrh to their patients as an effective, non-prescription relief option.
Our topical analgesic offers effective relief for most people, but results can vary. Individual responses depend on many factors like individual health conditions and the nature of the pain. While many users experience significant benefits, some may not find it as effective. Suitable for sensitive skin. Adults and children 12 and over.
This blend brings a rich, fragrant aroma from high-grade essential oils.

Australian Dream Arthritis Pain Relief Cream - Soothing & Non-Greasy - Powerful Topical Arthritis Pain Relief - Good for Muscle Aches or Joints - 4 oz Jar

Australian Dream

Australian Dream Arthritis Pain Relief Cream - Soothing & Non-Greasy - Powerful Topical Arthritis Pain Relief - Good for Muscle Aches or Joints - 4 oz Jar

Soothing and effective pain relief.
Economical with a small amount.
Odorless, non-greasy, and comfortable.

Main Highlights

Soothing Pain Relief: Our Australian Dream Arthritis Pain Relief Cream is easily absorbed, providing a powerful, effective formula for muscle and joint pains
Powerful, Economical Relief: Our cream provides a powerful solution to your arthritis pain, and it doesn't take much to do the job
Odorless & Non-Greasy: Our arthritis pain relief cream is non-greasy, odorless, and doesn't burn, making it perfect for sore muscles and painful joints
High-Quality Formula: With histamine dihydrochloride, this pain cream provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains, and bruises
Moving is Living: Australian Dream is dedicated to relieving pain and promoting comfort; this dedication is why we’re America’s first premium topical analgesic pain reliever

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g

Powerful topical pain relief.
Clinically proven effectiveness.
Easy to use and apply.

Main Highlights

One 5.3 oz/150 g tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
Number 1 Doctor Recommended topical pain relief brand
Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
Significant Arthritis Pain Relief, within seven days of continuous use and long-lasting relief when applied four times a day; apply on up to two joints at the same time for hand pain, wrist pain, elbow pain, ankle pain, foot pain or knee pain relief
Paraben and Dye-Free, Voltaren diclofenac gel is a non-greasy and clean scented gel
Voltaren Arthritis Pain Gel comes in a tube with flip cap and includes dosing card for proper dosage
HSA and FSA eligible product

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g Tube And 20 g Travel Size Tube

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g Tube And 20 g Travel Size Tube

Powerful relief from arthritis pain.
Doctor recommended for effectiveness.
Non-greasy and easy to apply.

Main Highlights

One 3.5 oz/100 g tube and one 0.71 oz/20 g travel size tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
Number 1 Doctor Recommended topical pain relief brand
Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
Significant Arthritis Pain Relief, within seven days of continuous use and long-lasting relief when applied four times a day; Apply on up to two joints at the same time for hand pain, wrist pain, elbow pain, ankle pain, foot pain or knee pain relief
Paraben and Dye-Free, Voltaren diclofenac gel is a non-greasy and clean scented gel
Voltaren Arthritis Pain Gel comes in a tube with flip cap and includes dosing card for proper dosage as well as a 20 g trial tube
HSA and FSA eligible product

Hempvana Arthritis Pain Relief Gel, Ultra-Strength for Arthritis in Muscles & Joints. Enriched with Hemp Seed Oil, AS-SEEN-ON-TV. Non-Greasy. Targeted Long-Lasting Arthritis Relief. Works Fast, 4 Oz.

Hempvana Arthritis Pain Relief Gel, Ultra-Strength for Arthritis in Muscles & Joints. Enriched with Hemp Seed Oil, AS-SEEN-ON-TV. Non-Greasy. Targeted Long-Lasting Arthritis Relief. Works Fast, 4 Oz.

6% OffFree Shipping

Ultra-moisturizing Hemp Seed Oil.
Targets pain right where needed.
Fast relief with non-greasy formula.

Main Highlights

HEMP SEED OIL: our Hempvana Arthritis Pain Gel is enriched with ultra-moisturizing Hemp Seed Oil
ULTRA-STRENGTH: to give you powerful relief from inflammation, swelling, and stiffness caused by arthritis
TARGET THE PAIN: our Ultra-Strength Relief Gel targets pain right where it hurts, like your hands, fingers, and wrists. Plus other arthritic joints
UNIQUE FORMULA: made with 100% pure cold-pressed hemp seed oil and FDA-listed pain-fighting menthol for active pain relief
NON-GREASY: Unlike other ointments that leave a greasy mess, Hempvana is non-greasy and absorbs quickly
FAST RELIEF: Targets muscle and joint pain associated with arthritis
COOLING RELIEF: made with soothing aloe and ultra-strength menthol to instantly cool the pain
MANUFACTURED IN THE USA: Purchase with confidence because Hempvana is manufactured in the USA in an FDA-inspected facility, safeguarded by GMP-certified practices
#1 BRAND: We are the #1 hemp pain brand in America based on 2022 AC Nielsen data

Amish Origins Arthritis Pain Relief Cream - 7 oz - Maximum Strength Deep Penetrating for Joint, Muscle, Knee, Back, Feet, Hand, Ankle, Aches, Neuropathy

Amish Origins Arthritis Pain Relief Cream - 7 oz - Maximum Strength Deep Penetrating for Joint, Muscle, Knee, Back, Feet, Hand, Ankle, Aches, Neuropathy

Fast relief from various pains.
Quick-acting and effective formula.
Greaseless, non-sticky application.

Main Highlights

Provides Fast Relief From Pain: Carefully Formulated With Active Ingredients That Target Pains, Amish Origins Deep Penetrating Pain Relief Cream Is Formulated To Provide Long-Lasting Relief From Pains Associated With Arthritis, Aching Joints, Sore Muscles, Restless Legs, Bruises, Sprains, Backache And More.
Quick-Acting Pain Relief Formula: Amish Origin Medicated Pain Relief Cream Has Earned Its Reputation As One Of The Best On The Market, And That’S Because It Delivers On Its Promises. As A Powerful Pain Relief Cream, Amish Origins Pain Relief Cream Absorbs Quickly And Delivers Fast Relief From Pain.
Greaseless Formula: While Other Pain Relief Formula Leave Behind Annoying Greasy Residues After Application, Not Amish Origins. This Is Because Amish Origins Is Carefully Formulated To Deeply Penetrate The Skin Without The Greasy Feel.
Easy To Use: This Pain Relief Cream Is Easy To Use. Simply Apply A Little Amount Topically, Wherever You Feel Pain, And Watch The Magic Unfolds.
Specially Formulated: To Provide Quick, Therapeutic, And Deep Soothing Relief From Pain, Amish Origins Deep Penetrating Pain Relief Cream Is Perfect For Treating Aching Joints, Restless Legs, Bruises, Arthritis, Headache, Muscle Strains, Backache, Sprains And More.
Target Gender: Unisex
Manufactured in USA

HealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)

HealthCareAisle

HealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)

29% OffFree Shipping

Clinically proven arthritis relief.
Targets pain directly at source.
Comparable to national brand quality.

Main Highlights

Arthritis pain relief medicine: Diclofenac Sodium Topical Gel 1% is clinically proven to relieve arthritis pain
Diclofenac Sodium Topical Gel 1% is a Non-Steroidal Anti-Inflammatory Drug (NSAID) that provides temporary relief of arthritis pain by penetrating the skin to target painful inflammation in the hand, wrist, elbow, foot, ankle and knee
Comparable to the national brand: Has the same active ingredient in Voltaren Arthritis Pain Gel* (Based on "Nair B, Taylor-Gjevre R. A Review of Topical Diclofenac Use in Musculoskeletal Disease. Pharmaceuticals (Basel). 2010 Jun 11;3(6):1892-1908")
Apply 4 times per day for up to 21 days to temporarily relieve arthritis pain or as directed by your doctor; do not use on more than 2 body areas at the same time; See package label for warnings, directions and other important information; use only as directed
HSA or FSA Eligible

Amazon Basic Care Arthritis Pain Relieving Gel, Diclofenac Sodium Topical Gel, 1% (NSAID), 5.29 Oz (150 Grams) (Packaging may vary)

Amazon Basic Care

Amazon Basic Care Arthritis Pain Relieving Gel, Diclofenac Sodium Topical Gel, 1% (NSAID), 5.29 Oz (150 Grams) (Packaging may vary)

Effective pain relief formula.
Clinically proven results.
Easy to apply gel.

Main Highlights

ACTIVE INGREDIENT: This arthritis pain reliever contains diclofenac sodium, an NSAID (non-steroidal anti-inflammatory drug) 1 percent (equivalent to 0.93 percent diclofenac); compare to the active ingredient in Voltaren Arthritis Pain
ARTHRITIS PAIN RELIEF: For the temporary relief of arthritis pain ONLY in the following areas: hand, wrist, elbow (upper body areas); foot, ankle and knee (lower body areas)
FOR DAILY ARTHRITIS PAIN: Use Amazon Basic Care Arthritis Pain Relieving Gel daily for the treatment of arthritis pain to keep you going strong; clinically proven to relieve arthritis pain
ANTI-INFLAMMATORY: Amazon Basic Care Arthritis Pain Relieving Gel contains an NSAID (non-steroidal anti-inflammatory drug) to help relieve hand, wrist, elbow, foot, ankle and knee arthritis pain
HOW TO USE: For arthritis pain only; use 4 times a day; may take up to 7 days to work for your arthritis pain; for use on no more than 2 body areas; use up to 21 days unless directed by your doctor; see product labeling for full directions prior to use

Boiron Arnicare Arthritis Cream for Minor Joint and Muscle Pain or Stiffness from Arthritis, Minor Injuries, Overexertion, or Repetitive Motions - 2.5 oz

Boiron Arnicare Arthritis Cream for Minor Joint and Muscle Pain or Stiffness from Arthritis, Minor Injuries, Overexertion, or Repetitive Motions - 2.5 oz

Effective dual action relief.
Quick absorbing, non-greasy formula.
Natural plant-based ingredients used.

Main Highlights

DUAL ACTION: Scientifically formulated with Arnica Montana and Harpagophytum (Devil’s Claw) for dual action pain relief. Addresses minor arthritis pain at its source and is suitable for use on all joints.
TOPICAL PAIN RELIEF: The non-greasy light, silky texture quickly absorbs into skin is ideal for sudden flare-ups and soreness.
PLANT-BASED ACTIVE INGREDIENT: Arnica Montana and Harpagophytum are natural pain relievers. No camphor, menthol, or other ingredients that cause burning or stinging and is paraben-free.

BLUE-EMU Maximum Pain Relief Cream for Arthritis, Muscle, & Joint Aches, 3 Oz, 1 Pack

BLUE-EMU Maximum Pain Relief Cream for Arthritis, Muscle, & Joint Aches, 3 Oz, 1 Pack

Targets any area needed.
Fast-acting relief for active lifestyles.
Safer alternative to traditional options.

Main Highlights

Our formula works wherever you need it, from your overworked shoulders to your hardworking feet
Blue-Emu Maximum Pain Relief Cream delivers fast-acting relief that keeps up with your non-stop lifestyle
Our cream offers a safer alternative to diclofenac, providing powerful relief without the same risk of side effects
Our odorless formula tackles arthritis pain without announcing your discomfort to the world
Our fast-absorbing formula doesn't leave you feeling slick because we know you're here to tackle life, not slide through it