10 Best Remineralizing Toothpaste of 2025

Last updated on 07/20/2025

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Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Remineralizing, Natural, Sensitive Teeth, SLS Free, Xylitol Nano-Hydroxyapatite Toothpaste for Adults, Mint 4oz (USA Made)

Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Remineralizing, Natural, Sensitive Teeth, SLS Free, Xylitol Nano-Hydroxyapatite Toothpaste for Adults, Mint 4oz (USA Made)

NASA-inspired enamel repair technology.
Clinically proven 10% effectiveness.
Fluoride-free and safe for everyone.

Main Highlights

NASA-INSPIRED ENAMEL REPAIR: Developed from NASA's space research, our 10% Nano Hydroxyapatite toothpaste restores and strengthens enamel, better than fluoride, without the harmful side effects. Achieve next-level protection and care for your teeth with every brush.
CLINICALLY PROVEN 10% NANO HYDROXYAPATITE: Unlike other brands that hide their Nano-Hydroxyapatite percentages, our toothpaste contains the full 10% Nano Hydroxyapatite—the clinically proven amount required for effective enamel restoration. Our nano-sized particles are precisely engineered to fill the microscopic pores in your teeth, delivering superior remineralization and protection.
NATURAL WHITENING, NO SENSITIVITY: Say goodbye to harsh bleaching agents. Our nano hydroxyapatite toothpaste smooths and whitens teeth by filling micro-lesions in the enamel, leaving you with a glossier, brighter smile—without causing sensitivity.
FLUORIDE FREE & SAFE FOR ALL AGES: Our toothpaste is completely fluoride-free, offering a safe alternative for those looking to avoid the negative health impacts of fluoride. Our nHa toothpaste is made with biocompatible ingredients, safe if swallowed and recommended by dentists nation-wide.
MADE IN USA WITH CLEAN, NATURAL INGREDIENTS: Made in the USA with premium, natural ingredients. Our toothpaste is fluoride-free, SLS-free, with birch xylitol to promote oral health. No artificial colors or flavors—just clean, gentle care for your mouth.

Designs for Health Periobiotic Silver Hydroxyapatite Toothpaste - Fluoride Free Toothpaste with Oral Probiotics with Whitening Hydroxyapatite - Supports Gum Health & Remineralization (4oz Mint)

Designs for Health

Designs for Health Periobiotic Silver Hydroxyapatite Toothpaste - Fluoride Free Toothpaste with Oral Probiotics with Whitening Hydroxyapatite - Supports Gum Health & Remineralization (4oz Mint)

Strengthens tooth enamel naturally.
Supports healthy gum microbiome.
Gentle, sulfate-free foaming action.

Main Highlights

Whitening Hydroxyapatite, Suitable for Sensitive Teeth - This non fluoride toothpaste formulated with the most unique combination of ingredients to support tooth enamel strength, overall oral health, gum health and a sparkling, brighter smile.
Supports Natural Remineralization - Features hydroxyapatite and hydrated silica to help promote natural remineralization and a bright smile. Incorporating calcium hydroxyapatite into your daily routine may help promote healthy tooth enamel and overall shine.
Probiotic Oral Microbiome & CoQ10 Healthy Gums Support - Probiotic toothpaste can support oral microbiome balance. It also contains purified silver to support oral wellness and CoQ10 to promote healthy gums.
Gentle Foaming Action Without Sulfates - This SLS free toothpaste uses coco-betaine sourced from coconuts instead of traditional sulfates for foaming and cleansing so you get the best of both worlds: a non-gritty, foaming toothpaste in a gentle formula.
Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**

JUST INGREDIENTS Remineralizing Tooth Powder | Fluoride-Free Hydroxyapatite Formula | Supports Enamel Strength & Oral Wellness | Safe, Clean Ingredients | Cool Mint Flavor

JUST INGREDIENTS

JUST INGREDIENTS Remineralizing Tooth Powder | Fluoride-Free Hydroxyapatite Formula | Supports Enamel Strength & Oral Wellness | Safe, Clean Ingredients | Cool Mint Flavor

Strengthens enamel effectively.
Natural whitening for brighter smiles.
Safe, clean, handpicked ingredients.

Main Highlights

SCIENCE-BACKED STRENGTH: Our fluoride-free tooth powder features hydroxyapatite, a research-supported mineral shown to help strengthen enamel, protect teeth, and support overall oral health for a resilient, vibrant smile.
NATURAL WHITENING: Our tooth powder combines hydroxyapatite and bentonite clay to help gently remove surface stains, revealing a naturally brighter, healthier-looking smile with every brush.
ENAMEL SUPPORT: Our mineral-rich formula featuring hydroxyapatite is designed to help replenish essential minerals and support strong, healthy enamel, promoting lasting comfort and oral wellness.
HEALTHY, HANDPICKED INGREDIENTS: Made with safe, clean ingredients you can trust, including calcium carbonate, xylitol, and essential oils like spearmint and wintergreen. Our fluoride-free formula offers a natural, refreshing approach to daily oral care.
WHOLE-BODY WELLNESS: Developed by Dr. Michelle Jorgensen, a dentist committed to holistic wellness, our tooth powder prioritizes your entire body's health. With years of expertise in dentistry and naturopathy, Dr. Jorgensen has created a safe alternative to toothpaste that promotes holistic well-being.
THIRD-PARTY TESTED: Living Well with Dr. Michelle products are rigorously tested for heavy metals and trace elements to ensure purity and safety. Our Whitening Tooth Powder meets strict quality standards and has been verified to comply with California Proposition 65 exposure limits.

Uncle Harry's Peppermint Remineralizing Toothpaste | Natural Whitening, Freshens Breath & Promotes Enamel | Vegan Fluoride Free (2 Pack)

Uncle Harry's Peppermint Remineralizing Toothpaste | Natural Whitening, Freshens Breath & Promotes Enamel | Vegan Fluoride Free (2 Pack)

Freshens breath with natural ingredients.
Strengthens enamel with essential minerals.
Whiten teeth without harsh chemicals.

Main Highlights

FRESH BREATH － An all natural toothpaste that eliminates bad breath with fresh peppermint and refreshes your mouth with mineral clays, sea salt, and pure plant essences all day long. Uncle Harry's Natural Tooth Paste Products come packaged in an Earth-friendly, zero waste glass jar that’s been labeled by hand.
STRENGTHEN TEETH － Save your teeth and gums with Uncle Harry's remineralizing toothpaste formula. It encourages healthier tooth enamel by nourishing teeth with calcium, magnesium, and phosphorus. It also helps maintain a naturally alkaline pH that is best for oral health and dental hygiene.
NATURAL TEETH WHITENING － Ditch the whitening strips and avoid increased tooth sensitivity. Our natural toothpaste whitening formula helps you feel confident that you're polishing and perfecting your teeth without harsh chemicals.
SUSTAINABLE TOOTHPASTE INGREDIENTS － Uncle Harry’s natural toothpaste contains only natural, minimally processed ingredients for your family. Bentonite clay, calcium carbonate, colloidal silver, sea salt, mustard seed, eucalyptus, clove, wintergreen, and oregano essential oils.
CLEAN & QUALITY － Uncle Harry's oral care remedies are proudly SLS free, gluten free, glycerin free, fluoride free, and vegan to meet even the most sensitive and conscious tooth needs. Our 100% natural toothpaste products are also made without synthetic preservatives like foaming agents, colors, artificial flavors, or baking soda.

APAGARD® PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2

APAGARD® PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2

Naturally beautiful teeth enhancement.
Effective plaque removal formula.
Family-friendly for all ages.

Main Highlights

APAGARD, Japan's leading toothpaste series for naturally beautiful teeth, is now available in the US. Discover the secret of naturally beautiful teeth from Japan. Contains Sangi's original nano-hydroxyaptite (nano-mHAP), almost the same substance as the hydroxyapatite that our teeth are made of, first synthesized in the 1970s by Sangi Co., Ltd
APAGARD cleans the teeth and helps remove plaque with regular brushing.
APAGARD M-plus is the standard, classic version and longest-selling product in the APAGARD range. It offers an all-around balance between natural whiteness enhancement, breath care, and stain control, and is suited for all ages, coming in a higher volume package, ideal for family use.
For the best effect from nano-mHAP toothpaste, we recommend that you (1) Place a small amount (1-1.5 cm) on a toothbrush. (2) Brush your teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal (3 times/day is recommended) (3) Rinse lightly and spit out after brushing, so nano-mHAP remaining will enrich your saliva and continue its work.

Simply Sooney Fluoride Free Remineralizing Toothpaste Powder I Vegan I Gluten Free I Organic Peppermint Essential Oil 1.5oz

Simply Sooney Fluoride Free Remineralizing Toothpaste Powder I Vegan I Gluten Free I Organic Peppermint Essential Oil 1.5oz

7% OffFree Shipping

Vegan ingredients for eco-conscious consumers.
Mineral-rich for gentle whitening.
Refreshing peppermint flavor for freshness.

Main Highlights

Vegan Formula: This tooth powder is made with vegan ingredients and is free of Bisphenol A (BPA).
Mineral-Rich: Contains bentonite clay and other minerals to gently whiten teeth.
Fluoride-Free: This tooth powder does not contain fluoride, which can be harmful in high doses.
Peppermint Scent: The tooth powder has a refreshing peppermint flavor that leaves teeth feeling clean.
Organic Ingredients: Made with organic ingredients like peppermint oil and essential oils.

RiseWell Mineral Toothpaste - All Natural Toothpaste with Hydroxyapatite - Made in The USA, No Added Fluoride, SLS-Free - for a Stronger and Healthier Teeth, Wild Mint, 3.4 Oz

RiseWell Mineral Toothpaste - All Natural Toothpaste with Hydroxyapatite - Made in The USA, No Added Fluoride, SLS-Free - for a Stronger and Healthier Teeth, Wild Mint, 3.4 Oz

Natural enamel strengthening formula.
Sensitive teeth relief guaranteed.
Travel-friendly and clean ingredients.

Main Highlights

REMINERALIZE AND SHINE WITH EVERY BRUSH: Our SLS free toothpaste with no added fluoride has Hydroxyapatite that strengthens enamel, naturally whitens teeth without harsh abrasives, and helps remineralize teeth. This natural sensitive toothpaste reduces sensitivity while delivering effective remineralization.
SENSITIVE TEETH RELIEF: Experience natural protection with our clean toothpaste for sensitive teeth! Unlike other toothpastes, this hydroxyapatite toothpaste uses hydroxyapatite to reduce sensitivity while remineralizing tooth enamel. For a stronger and healthier smile, try our hydroxyapatite-toothpaste.
100% CLEAN & TRAVEL-READY: This travel toothpaste is TSA-approved at 3.4 oz toothpaste, making it easy to take anywhere. Formulated to remineralize teeth, this no added fluoride toothpaste is free from sulfates, parabens, and artificial additives—pure, safe, and always ready remineralize toothpaste for your next trip!
LONG-LASTING NATURAL DENTIST TOOTHPASTE: This 3.4oz tube of remineralizing toothpaste with hydroxyapatite lasts approximately 3 months when used twice daily, a good toothpaste that provides continuous oral care without running out. Try RiseWell's hydroxyapatite whitening toothpaste!
MADE IN THE USA MINERAL TOOTHPASTE: RiseWell's hydroxyapatite whitening toothpaste is proudly manufactured in the USA. This natural whitening toothpaste is cruelty-free, vegan, and gluten free toothpaste. This made by dentist toothpaste offers a clean, ethical option for those who care about what goes into their oral health routine.

Nano hydroxyapatite Toothpaste Fluoride Free | Pro Remineralizing Toothpaste Plus Anti Cavity Xylitol – Dentist Formulated Tooth Remineralization for Sensitive Teeth & Enamel Support in Wintermint

Great Oral Health

Nano hydroxyapatite Toothpaste Fluoride Free | Pro Remineralizing Toothpaste Plus Anti Cavity Xylitol – Dentist Formulated Tooth Remineralization for Sensitive Teeth & Enamel Support in Wintermint

Clinically tested enamel repair.
High-quality ingredients only.
Long-lasting concentrated formula.

Main Highlights

WE COST MORE, WHY? One, we don’t use cheap fillers. Most other brands list glycerin among their main ingredients. Glycerin is just a filler which, in larger quantities, clings to enamel, inhibits calcium absorption & can attract plaque. Two, we use the highest quality nano-hydroxyapatite which has been clinically tested for effective enamel repair & sensitivity relief. Three, our concentrated formula makes this the economical choice, it lasts longer as you only need a pea sized dab.
ENAMEL REPAIR TOOTHPASTE WITH HYDROXYAPATITE: Hydroxyapatite is a naturally occurring form of calcium that forms over 90% of a tooth’s enamel. Thanks to its ability to fill in and repair enamel damage, it is great for a remineralizing toothpaste. Plus, as hydroxyapatite is pure white, it adds gentle and non-abrasive whitening to your teeth. With a high concentration of two forms of hydroxyapatite, our holistic toothpaste provides superior remineralization and sensitivity relief.
SUPERIOR TOOTH REMINERALIZATION: Our mineralizing toothpaste has a low RDA (relative dentin abrasivity) of 87 & a pH range of 7.2 - 7.4 for optimal enamel protection. With an 11% concentration of a unique bioavailable nano and non-nano hydroxyapatite formulation, our dentist researched formulation targets sensitivity and remineralization from two paths using the nano to dig deep into your damaged enamel and the non-nano hydroxyapatite to support your saliva’s natural mineralization process.
DENTIST FORMULATED AND MADE IN THE USA: Researched for over 7 years by one of the nations top holistic dentists, this formulation is designed to support the health of your entire oral cavity. His practice and philosophy follows a biomimetic approach to health–biomimetic means to use techniques that imitate and use nature’s own patterns for healing and health. Your mouth is the gateway to your body and your best health starts with great oral health.
POTENT INGREDIENTS: Our nano-hydroxyapatite toothpaste is packed with Xylitol for anti-cavity properties, organic aloe for natural healing, sea salt to tighten gums + is gluten, soy, dairy & glycerin free!* This sensitive toothpaste is also free of harsh whiteners, SLS, petroleum or animal products making it a vegan friendly toothpaste. *New production as of Jul 2024 is glycerin free however, please note you may still receive a unit with trace amounts of glycerin until our inventory is fully turned over.

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Refresh Mint Flavor, 4 Fl Oz 1Pk

Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Refresh Mint Flavor, 4 Fl Oz 1Pk

27% OffFree Shipping

Enhances gum health remarkably.
Whitening teeth for brighter smiles.
Gentle solution for sensitive teeth.

Main Highlights

APPROPRIATE FOR GUM HEALTH & ENAMEL REPAIR: A powerhouse next generation formula for gum health by harnessing the strength of Nano Hydroxyapatite (NHA)!
REMINERALIZES & WHITENS TEETH: Thanks to its innovative formula with Nano Hydroxyapatite (NHA), our toothpaste not only effectively cleans your teeth but also aids in the remineralization process. As a result, it improves your overall tooth enamel health and helps to brighten those pearly whites
BIOCOMPATIBLE: Free from Fluoride, Sulfates, Parabens & Artificial Flavors & Colors - we meticulously crafted our product to be 100% biocompatible, ensuring it’s safe for daily use and non-toxic when used as directed. A perfect way to take your oral hygiene routine to the next level!
APPROPRIATE FOR SENSITIVE TEETH: Gentle yet effective, it provides a soothing and refreshing experience for the whole family. Embrace an oral care routine designed for a luxurious experience
MINTY FRESH: We complemented n-HA with our soothing aloe vera, bacteria fighting xylitol, antioxidant-rich green tea, and refreshing mint, to give this paste a refreshing and invigorating flavor profile.

Davids Hydroxi Fluoride Free Nano Hydroxyapatite Toothpaste for Remineralizing Enamel & Sensitive Relief, Whitening, Antiplaque, SLS Free, Natural Peppermint, 4 oz, Made in USA

Davids Hydroxi Fluoride Free Nano Hydroxyapatite Toothpaste for Remineralizing Enamel & Sensitive Relief, Whitening, Antiplaque, SLS Free, Natural Peppermint, 4 oz, Made in USA

Natural ingredients for effective whitening.
Enhanced enamel protection and remineralization.
Gentle on sensitive teeth and gums.

Main Highlights

Features Hydroxi, our proprietary formulation of Nano Hydroxyapatite (n-HA) - the same ingredient that naturally makes up 97% of your teeth material, and carefully selected naturally sourced and naturally derived ingredients. We eliminated the fluoride and replaced it with this biocompatible ingredient to remineralize your enamel, reduce teeth sensitivity and naturally whiten.
Safe & Gentle Whitening – micro polishing agents gently remove surface stains to safely whiten without causing the sensitivity normally found with peroxide or other bleaching agents. RDA (abrasive rating) of 101 to effectively remove plaque and surface stains while being enamel safe for daily brushing. Safe range per ADA (American Dental Association).
Bioactive Sensitive Relief - most sensitive toothpastes uses Potassium Nitrate (nerve numbing drug) to temporarily numb the tooth nerves. We use Hydroxyapatite (n-HA) to reduce sensitivity by remineralizing the enamel and passageways (tubules) to the nerves.
Clean & Safe Ingredients – we use only premium ingredients derived from plants and the earth, with no animal by-products (vegan). Fluoride Free, Sulfate Free (no SLS), EWG VERIFIED. No Artificial Flavors, Colors, or Preservatives. Birch xylitol used to improve oral health.
Healthy Mouth – formulated to restore a healthy PH balance and support your mouth’s natural oral microbiome. Plaque is the main enemy of teeth and Davids is designed to aggressively stop plaque from forming and reduce existing plaque buildup, while leaving your mouth feeling minty fresh and exceptionally clean. Healthy mouth for a healthy you.